Infectious Disease Flashcards
what is an infectious disease
any disease caused by invasion by a pathogen that grows and multiplies in the body
what / who infectious disease impact
-animals
-producers
-regional trade
-national trade
-international trade
-trade policies
infectious agents
-viruss
-bacteria
-fungal
-parasites
-protozoa
-prions
contagious meaning
an agent capable of being spread from one indiv to another
types of infections
- primary
- oppurtunistic
- adventitial
primary pathogens
causes disease among normal (healthy) individuals
opportunistic pathogens
cause disease only to indiv whos innate and/or acquired immune system is compromised
adventitial pathogens
cause in fection by acccident
how are nomenclatures determined for infections
- site of infection
- route of pathogen acquisition
- virulence
site of infections classifications
- superficial
- cutatneous
- subcutaneous
- systemic
-infections depend on the degree and involvement of the pathogens w body tissues ex. its more serious if the pathogen is in systemic (organs) rather than superficial (surface of skin)
routes of acquisition
- endogenous
- exogenous
exogenous pathogen routes for entry
comes from outside the body
ex. airborne, cutaneous or percutaneous
virus def
-one of the smallest life forms
-replciating microorganism
- simplicity = obligate reqs for intracellular growth and heavy dependence of host-cell structure and metabolic components
virus characteristics
- collections in nucleic acid, protein and some lipid
virion
complete virus particle
virus goal
transfer nucleic acids from one cell to another
-each has individual methods to enter and then exit the cell
-can rupture the cell on exit and lyses the cell (a bud) and have infection latency (from the cell lysing)
what do we know about viruses
-replication
-tissues tropism
-intracell mechs
-pahtogenesis
what type of viruses are the most virulent
viral infections that ere once considered eradicated and re emerging
virus contagiousness
-can spread local (cell to cell)
- can spread freely thru blood and lymphatic system
- can be primary oppor or advent
rinderpest
-primary pathogen (virus)
-PARAMYXOVIRUS (call it by this)
-peste de petits ruminant
-distemper
-measles virus same type
-“cattle plague”
rinderpest impacts
- mortality 100% in naive animals
-200 mill dead in 18th century
-75-225 mill African species dead - napoleon bonaparte’s conquest
rinderpest clinical signs
-depressed
-diarrhea w or wo hemorrhage
-gaunt
-dehydration
-oral lesions = starvation
-intestinal lesions
-necrosis
-congestion
-hemorrhage
-epithelium effects
rinderpest outside alimentary system
-extra alimentary lesions
- immune depression
-respiratory lesions
hwo to control and prevent viruses
1.vaccination
- target specific or immunomodulants
-prblem: all easy viral vaccines are produced
2.antimicrbls: anti viral but not practical in livestock
3. quarantine
- problem: non reporter vaccine
4. test and slaughter
-seropositive animals euthanized and whole farms or regions
5. trade restrictions
- exotic diseases that decimate agriculture ex. FMD, rinderpest, newcastle’s and public health concerns ex. influenza