Infectious Disease Flashcards
First Line Treatment Chlamydia?
If Prego?
Neonate Conjunctivitis?
- Doxy 100 mg BID x 7 days
- Prego = Azithromycin 1g
- Neonate = Erythromycin
What is Gonorrhea?
Gram Negative Diplocci
Yellow Green Discharge of anus/vagina/penis/pharynx?
Gonorrhea
Gonorrhea Arthritis Dermatitis Syndrome?
Disseminated Gonorrhea
- Tendon/Joint pain
- Rash
- Septic Arthritis (knee most common)
Tender Grey/Neurotic center Halo papules?
Gonorrhea gone Septic!!!
Treatment of Gonorrhea:
1st Line Healthy?
Septic?
What else should you give?
- I.M. Ceftriaxone
- Septic = I.V. Ceftriaxone
You should give DOXY to cover Chlamydia!
What is Cat Scratch Fever?
Bartonella Henselae
Describe onset of Cat Scratch Fever
Brown/red ulcers (2-4 weeks)
Fever (7 weeks)
Lymphadenopathy (2-4 months)
Treatment for Cat Scratch Fever
Moderate vs Severe
Moderate : Doxy
Sever : Rifampin
What is Clostridium Botulinum
Gram + anaerobe with spores
Clostridium Botulinum: with what prevents AcH release causing issues on Cranial Nerves
The Snare Protein Cleaver
Clostridium Botulinum Test:
Toxin Assay
Clostridium Botulinum Treatment
If immediate, Active Charcoal and Antitoxin A/G within 72 hours / Human Botulinum immunoglobulin
Which direction does Clostridium Botulinum move?
Head down to Feet
Describe Campylobacter Jejuni
Gram Negative Rod
Oxidase Postive
Flagella + Curved corkscrew shaped
Bloody Stool with Ascending paralysis?
Campylobacter Jejuni
Most Common Acute Bacteria : Campylobacter Jejuni, where to get it from? (4)
- Raw Chicken
- Unpastorized Milk
- Puppy Poop
- Pigs
D/X: Campylobacter Jejuni
Camp in the Heat (42 Degree Agar)
T/X: Campylobacter Jejuni? (2)
Fluoroquinolone or Azithromycin
Describe Vibrio Cholera
Gram Negative
Oxidase Postive
Comma Shaped (curved)
Glucose Fermenting
NonLactose
Rice Water Diarrhea?
Vibrio Cholera
D/X: Vibrio Cholera
Dipstick or Stool
T/X: Vibrio Cholera
Fluids + Doxy
Describe Diphtheria?
Gram + Rod Anaerobe
How does Diphtheria enter body?
Inhaled POOP
Diphtheria:
- Pseudomemberous?
- Lymphadenapathy?
- Myocarditis?
- Polyneuritis
- Patchy grey/white exudate that bleeds when scraped
- Bull Neck Cervical Lymph
- EKG + Enzymes
D/X: Diphtheria?
Elek Test
T/X: Diphtheria?
Antitoxin + Erythromycin
Describe a Boil/Pustule on skin with Methicillin Res. Staph A. (MRSA) patient?
Pustules w/erythematous base
D/X: MRSA
Normal Conditions?
OutBreak?
Normal - Chromogen Agar or PCR
Outbreak - PFGE
T/X MRSA: (Irrgate First)
Small:
Mod:
Severe:
Small: Mupirocin
Mod: Bactrim or Doxy
Severe: Vanco
Immune Response to Strep Pyrogens, my immune response mimics Anti-Strep-tolysin and fucks shit up?
Rheumatic Fever
Jones Criteria:
J.
O.
N.
E.
S.
Joints - (poly arthritis)
Heart - Carditis
Nodules
Erythema Marginatum
Sydenham Chorea
Involuntary hand/feet movement
Sydenham Chorea
Non-Puritic Trunk/Limb Rash
Erythema Marginatum
Rheumatic Fever:
- Common Valve Issue?
- Rhythm Issue?
- Found on Heart?
- Mitral Regurgitation
- A-Fib
- Aschoff Bodies
Direction of Joint Pain Rheumatic Fever?
Ankles/Knees moving up
Minor Criteria Jones?
C
A
F
P
CRP/ESR increased
Arthralgia
Fever
Prolonged PR Interval
T/X Rheumatic Fever:
1st Line:
Allergy:
PCN G or Amoxy
If Allergy - Erythromycin
Dermacentor Tick causes?
Rocky Mountain Fever - Rickettsia Rickettsii
D/X Rocky Mountain Fever?
Fever/HA
Wrist/Angle Rash that moves to Trunk
T/X: Rocky Mountain Spotted Fever
Doxy 200 mg x 7 Days
Describe Clostridium Tetani?
Gram + Rods Anaerobe
Clostridium Tetani, what does Tetanspasmin Exotoxin block on the pre synapse of motor nerves?
GABA and Glycine
S/S Clostridium Tetani
1.
2.
3.
- Lockjaw (trismus)
- Risus Sardonicus (raised eyebrow/grin)
- Opisthotunus (Head/Neck/Back Hyperextension)
Risus Sardonicus (raised eyebrow/grin)
Opisthotonus (Head/Neck/Back Hyperextension)
T/X: Clostridium Tetani
Metronidozol
Gram Neg
Oxidate Neg
NonLactose
White/HighPH (MaConkay)
H2S producing
Salmella
Gram Neg
Oxidate Neg
NonLactose
White/HighPH (MaConkay)
NOT H2S producing
Shigellosis
Salmonella from contaminated food
S. Typhi
Salmonella from fecal matter on food that cause Gastroenteritis?
S. Typh / S. Enteritis
Invades Pyer Patch with PeaSoup Diarrhea?
Another noticeable Sign?
What if Sickle Cell?
Salmella Typhi
Rose Spots (Trunk)
Sickle = osteomyelitis
D/X Salmella?
Culture (Increased WBC but Decreased Platelets)
T/X Salmella?
Fluids
DO NOT give ABX due to prolonging poop!
Inhibits 60s Ribosomes?
Shigellosis Sonnei (most common USA)
Flexneri (developing country)
Daycare kids, crowded areas that causes watery, mucus bloody painful diarrhea?
Shigellosis
S/S Shigellosis (4)
- Diarrhea (watery, mucus, bloody) painful
- Cramps
- Tenesmus
- High Fever and Chills
D/X Shigellosis?
Culture Stool
T/X Shigellosis?
1.
2. >18 y/o
3. <18 y/o
4. Caution
- Fluids
- Bactrim
- Azithromycin
- Don’t give meds that stop diarrhea
Four Areas for Candidiasis?
- Vaginal
- Esophageal
- Oral
- Intertrigo
Vaginal Candidiasis
1. Describe -
2. KOH -
3. T/X -
- Itchy, erythema, CURD discharge
- KOH - Hyphae Budding
- Miconazole cream 1-7 days or Fluconazole
Esophageal Candidiasis
1. Most common?
2. EGD shows?
3. T/X?
- AIDS
- Linear erosion
- Fluconazole
Dysphagia, Reflux, Nausea with or w/o pain. Patient is AIDs positive. What do you think it is?
Esophageal Candidiasis
T/X Oral Thrush (candidiasis)
Nystatin
Describe Intertrgo Candidiasis?
Pruritic BEEFY red rash w/distinct scalloped borders and satellite region
T/X Intertrigo Candidiasis:
1.
2.
*If in blood?
- Keep Dry
- Ketoconazole w/ Hydrocortisone 2.5%
If in blood, treat with I.V. AmpB
AIDs/immunocomprimised / Acne like ulcers
Cryptococcosis
How to contract Cryptococcosis?
Inhaled budding yeast in soil/bird poop
Cryptococcosis will cause what most of the time?
Meningoencephalitis
Meningoencephalitis Cryptococcosis symptoms? (3)
AMS
HA
meningismus
India Ink Cyst?
What does CSF tapping show?
1.
2.
Cryptococcosis
- increased pressure, protein, lymph
2.decreased glucose
T/X Cryptococcosis?
1.
2. If CD4 < 100 prophylaxis
3. Pneumonia
- AmpB + Flucytosine 2 week followed by Fluconazole 10 weeks
- Fluconazole
- Fluconazole
Caseous Necrosis granulmoa?
histoplasmosis capsulatum
S/S (4)
- Cough
- Low grade Fever
- Tongue Ulcerations
- Huge Spleen
D/X histoplasmosis capsulatum?
1. Takes long time but GOLD Standard
What would you see?
- Urine Cultures
Increasing Alkaline Phosphatase LDH postive
T/X histoplasmosis capsulatum:
1. Weeks/Months?
2. IF systemic?
Itraconazole weeks/months
If Systemic AmpB
Interstitial pneumonia with ground glass opacities HIV patient?
pneumocystis jiroveci pneumonia
pneumocystis jiroveci pneumonia 3 common symptoms
Dyspnea
Fever
Non-productive Cough
D/X pneumocystis jiroveci pneumonia?
Respiratory Tract tissue sample or Broncho alveoli levaage
T/X pneumocystis jiroveci pneumonia?
1.
2. If allergy?
- Bactrim
- Pentamidine