Infectious Diarrhea Flashcards
Causative organisms of salmonellosis?
Salmonella bongori, salmonella enterica
Reservoirs of salmonellosis?
poultry (MC)
pet reptiles- turtles
Salmonellosis is associated with?
reactive arthritis - can’t see, can’t pee, can’t climb a tree
Causative organisms of Shigellosis?
Shigella dysenteriae (most aggressive)
Shigella sonnei- developed nations, milder disease
Shigella flexneri- less developed nation
Reservoirs of Shigellosis?
rapidly spreads in close quarters- military example
contaminated H20
food
produce grown where sewage used as fertilizer
Causative organisms of Campylobacter species?
Campylobacter jejuni
Reservoirs of Campylobacter species?
poultry (MC)- raw/uncooked animals and livestock
raw milk
chicken pate
domestic dogs and cats
Complications of Campylobacter species?
Guillain-Barre syndrome (ascending paralysis)
Reservoirs of enterohemorrhagic e. coli (EHEC)?
Cattle cows (MC)
Enterohemorrhagic e.coli (EHEC) is capable of producing what?
Shiga toxin-producing e. coli (STEC)
Reservoirs of Yersinosis?
Pigs
Infants and children w/ Yersinosis may progress to?
Necrotizing eterocolitis
Clinical manifestations of Yersiniosis?
mesenteric lymphadenitis-RLQ pain
Mimics appendicitis
Causative organisms pseuromembranous colitis?
clostridium difficile (c.diff)
Pseudomembranous colitis is usually associated with what antibiotics?
Clindamycin (MC)
Ampicillin
Cephalosporins (2nd and 3rd generation)
Fluoroquinolones
A severe case of Pseudomembranous colitis can result in?
Toxic megacolon
greenish, foul-smelling watery diarrhea
profuse diarrhea >30 x a day
What stool study is used for Pseudomembranous colitis?
Nucleic acid amplification test (PCR assay) for TcdB toxin-higher sensitivity
Lab findings for Pseudomembranous colitis?
Leukocytosis >30,000
Tx for Pseudomembranous colitis?
Metronidazole - 1st line for mild-moderate disease (caution w/ etoh intake)
Vancomycin (PO only NOT IV) - >2 occurrences, good for leukocytosis
Fecal transplant - if everything else false
Causative organisms of Amebiasis?
Entamoeba histolytica