Esophagus GI issues Flashcards

1
Q

What is esophagitis?

A

Inflammation of the esophagus primarily affecting the mucosa. Associated with GERD or other not infectious causes.

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2
Q

What is dysphagia?

A

Difficulty in swallowing caused by a number of underlying causes: stroke, local trauma, muscle dysfunction, tumor or swelling that obstructs the passage of food

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3
Q

List some neuromuscular causes of oropharyngeal dysphagia

A
CVA
MS
Thyroid dysfunction
CP
Head trauma 
Bells palsy
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4
Q

List some structural disorders that cause oropharyngeal dysphagia

A
Oropharyngeal tumors
Zenker's diverticulum 
Thyroidomegaly
Prior surgery/radiation
Prox. esophageal webs 
Cleft palate
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5
Q

List some neuromuscular causes of esophageal dysphagia?

A

achalasia
diffused esophageal spasm
nutcracker esophagus
scleroderms

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6
Q

List some structural disorders that cause esophageal dysphagia?

A
peptic stricture
esophageal rings and webs
diverticula
carcinoma
foreign bodies
mucosal injuries ---> infections or GERD
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7
Q

List dysphagia red flags

A
weight loss 
odynophagia
vomiting
early satiety 
GI bleeding 
Iron deficiency
---> carcinoma
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8
Q

When does oropharyngeal dysphagia begin?

A

begins within 2 seconds of swallowing

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9
Q

When does esophageal dysphagia begin?

A

begins several seconds after swallowing and often in a feeling of food being stuck in lower sternal area

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10
Q

What is the best test for esophageal dysphagia?

A

Esophagogastroduodenoscopy (EGD)

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11
Q

What is achalasia?

A

Motliltiy disorder of the esophagus characterized by incomplete relaxation of the lower esophageal sphincter and peristalsis of esophagus smooth muscle.
—-> failure to relax

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12
Q

Short term symptom relief of achalasia?

A

CCB and Nitrates

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13
Q

What is esophageal spasm?

A

increase number of uncoordinated peristaltic waves

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14
Q

What is esophageal stricture?

A

narrowing of the esophagus usually due to gastric reflux can be d/t toxic liquids or solids

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15
Q

What is an esophageal ring (schatzki ring)

A

narrowing of the diameter of the esophageal lumen usually at the level of the lower esophageal sphincter. This mucosal ring is a thin annual web-like tissue usually at the level of the squamocolumnar junction

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16
Q

What is esophageal web?

A

a thin membrane that may develop across the lumen of the esophagus usually at the level of the cricoid cartilage

17
Q

What is esophageal web associated with?

A

iron def. anemia.

18
Q

What is Zenker’s Diverticulum?

A

obstruction of the esophageal introitus that results from mucosal herniation posteriorly between the cricopharyngeus muscle and the inferior pharyngeal constrictor muscle.

19
Q

S/Sx of Zenker’s Diverticulum?

A

dysphagia to solids and liquids (MC)

regurgitation

sensation of lump/fullness

cough

halitosis

aspiration pneumonia

weight loss

voice changes

sialorrhea

20
Q

What is the test of choice to diagnose Zenker’s diverticulum?

A

Barium swallow

21
Q

What is a hiatal hernia?

A

protrusion of intra-abdominal contents through an enlarged esophageal hiatus of the diaphragm

22
Q

Barrett’s esophagus is predisposed to develop what?

A

esophageal adenocarcinoma

23
Q

Clinical sxs and findings of Barretts esophagus?

A

chronic hearburn

dysphagia w/ solid foods

epigastric TTP

24
Q

Etiology of Barretts esophagus?

A

metaplasia is thought to result from re-epithelialization of esophageal tissue injured as a result of chronic GERD

25
Red flag sxs with Barretts esophagus?
dysphagia odynophagia weight loss vomiting early satiety GI bleeding Iron deficiency
26
What is Mallory Weiss tear?
longitudinal mucosal laceration in the region of the gastroesophageal junction OR nonpenetrating tear of the gastroesophageal junction w/ hx of vomiting
27
Mallory Weiss tear DDx?
esophageal or gastric varices esophageal, gastric, duodenal ulcers gastric erosions A-V malformation neoplasms
28
Mallory Weiss tear hx/clinical findings?
hematemesis vomiting, retching, or vigeous coughing tachy hyoTN melana hematochezia Alcoholics
29
What are esophageal varices?
dilated submucosal vein that occurs in pts w/underlying portal HTN. Can results in sever upper GI hemorrhage
30
Clinical presentation of esophageal varices?
hematemesis hypovolemia palmar erythema telangiectasis gynecomastia caput medusea (abdominal varices)
31
What is some clinical presentation of Budd-Chiari syndrome?
IVC thrombosis w/ subsequent hepatocellular carcinoma (Africa and south Asia) primarily myeloproliferative disorders and underlying hypercoagulable states (United States)
32
Diagnostic/work up for Budd-Chiari syndrome?
US and color and pulsed doppler
33
Etiology of squamous cell esophageal neoplasm?
MC in African Americans
34
Etiology of adenocarcinoma esophageal neoplasm?
MC in whites
35
esophageal neoplasm ratio of males vs females?
3-4:1 ---> highest in the Hispanic population
36
Link between barretts esophagus and esophageal adenocarcinoma?
familiar clustering --> genetic link between the two
37
Clinical presentation of esophageal neoplasm?
Dysphagia (MC) Unintentional weight loss Hoarseness Cervical adenopathy Iron def. anemia hypercalcemia
38
Etiology of esophageal neoplasm?
Excess alcohol Tobacco obesity hiatal hernia high fat diet mucosal damage achalasia chronic GERD celiac sprue
39
How common is esophageal neoplasm and where does it rank in number of deaths worldwide?
8th MC cancer, 7th leading cause of cancer death worldwide.