Infectious causes of inflammatory joint disease

Question 1

Primary osteoarticular site for tuberculosis spread?

Answer 1

Spine is primary site for spread of ……

Question 2

Secondary site of TB spread?

Answer 2

Large joints, mainly hips and knees with pain and swelling over the course of weeks or months.

Question 3

Ten percent of extrapulmonary TB is where?

Answer 3

Osteoarticular TB

makes up what percentage of extrapulmonary TB

Question 4

The majority of patients with extra pulmonary TB have what on their chest X-ray?

Answer 4

Normal chest xray is found in majority of patients with what?

Question 5

How much of the world’s population is infected with TB?

Answer 5

One fourth of the world’s population

is infected with what?

Question 6

How does TB spread to joint and bone?

Answer 6

Hematogenous spread from primary infection
Lymphatic spread from distant focus
Contiguous spread from infected areas* (bone and joint combo)

Question 7

Why is synovial fluid a poor screening test for suspected TB in joint?

Answer 7

AFB smears of synovial fluid are only 20% sensitive for the detection of TB.

Question 8

What is most sensitive test for suspected TB in a joint?

Answer 8

Synovial biopsy

Most sensitive test for what?