Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

step 2ck > Infectious > Flashcards

Infectious Flashcards

1
Q

Beta lactam abx

A

PCN
carbapenems
aztreonam
cephalosporins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Beta lactam abx action

A

inhibit cell wall synthesis by blocking peptidoglycan crosslinking
–>Bactericidal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

beta lactam cns penetration

A

only ones are ceftriaxone and aztreonam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Beta lactam elimination

A

renally

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

beta lactamase inhibtors

CAST

A

Clavulanic Acid Sulbactam Tazobactam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

PCNs

Pencillin G and V clincial use

A

Gram-positive aerobes (streptococcus, enteroccus facecalis)
Gram Neg cocci Nesseria Menigitis
Sphriochetes (treponema pallidum)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Anti staphy PCNs
Nafcillin
Dicloxacillin
oxacillin

A

Gram positive aerobes –>MSSA

can cause intersitial nephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

AminoPCNs
Amoxicillin-clavulanate = Augmentin
Ampicillin-Sulbactam= Unasyn

Clinical use
sid effects are pseudobranous colitis (C. dif)

A 
HHELPSSS destory enterococci
H. pylori
H. influenzae
E. Coli
Listeria
Proteus
Salmonella
Shigella
Enterococci
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

UreidoPCNs

piperacillin-tazobacatm= Zosyn

A

Gram negative bacilli–> Pseudomnas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

A TICk kills Pseudomonas with a PIPE bomb in a CAR

A

TICarcillin
PIPEracillin
CARbenicillin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q 
Carbapenems =
Imipenem
Meropenem
Ertapenem
Doripenem
A

Broad spectrum
Cover everything except MRSA, enterococcus, legionella
ertapenem does not cover for pseudomonas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Carbapenems

adverse effects

A

Lower seizure threshold
GI upset
rash

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Monobactam= Aztreonam

A

Gram negative bacilli only (e. coli, klebsiella, proteus, pseudomonas)
synergistic wiht aminoglycosides
alternative for beta lactasmase resistance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

1st generation Cephalosprins=
Cephalexin–> Kefflex
cefazolin

A

GP- cocci (MSSA and Strep)
Proteus
E coli
Klebsiella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

2nd gen Cephalosporins=

cefaclor, cefuroxaime, cefoxitin, cefotetan

A 
GP- cocci (MSSA and Strep)
H influenza
Enterobacter
Neisseria
Proteus
E coli
Klebsiella
Serratia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

3rd gen Cephalosporins=

Cefixime, ceftriaxone, cefotaxime, ceftazidime

A

severe gram-neg infection
Ceftazidime good against pseudomonas
Ceftriaxone good CNS penetration and use in dissemianted lyme disease, gonrrhea

17
Q

4th gen Cephalosporin=

Cefepime

A

Gram-neg including pseudomonas

gram- pos MSSA (no MRSA)

18
Q

5th gen cephalosporins=

ceftaroline

A

gram positive with MRSA coverage

gram negative but not pseudomonas

19
Q

Cephalosporins can be LAME

A 
dont usually act against
Listeria
Atypical organisms (chlamydia, mycoplasma)
MRSA
Enterococci
20
Q

Cephalosporins side effects

A

hypersensitivity
Autoimmune hemolytic anemia
Vit K def
Disulfiram-like reaction

21
Q

Glycopeptides=

Vancomycin

A 
Bactericidal
Gram-positive bacteria only
MRSA
S. epidermidis
Enterococci
C. diff
22
Q

Vancomycin

side effects

A

nephrotoxicity
ototoxicity
Red man syndrome
thrombophlebitis

23
Q

Lipopeptides=

Daptomycin

A

Bactericidal
gram positive aerobes
MRSA except for lungs such as PNA because inactivated by surfactant
Vancomycin resistant enterococci

24
Q

Daptomycin side effects

A

myopathy and rhabdomyolysis

25
Q

Trypanosoma brucei is what and from where and transmitted by what

A

parasite
sub-saharan Africa
tsetse fly

26
Q

What type of diagnostic test must be done on all cases of African trypanosomiasis

A

lumbar puncture

27
Q

Clinical features of Trypanosoma brucei

A

Stage 1 fever with painless cervical lymphadenopathy in posterior triangle of neck (winterbottom sign)
stage 2
psychosis, somnolence, ataxia coma

28
Q

west african sleep sickness tx

A

stage 1 pentamidine

stage 2 eflornithine and nifurtimox

29
Q

east african sleeping sickness tx

A

stage 1 suramin

stage 2 melarsoprol

30
Q

Entamoeba histolytic is a what, found where, transmitted by?

A

Protozoan/ parasite
Mexico, SE asia, India
Fecal oral route

31
Q

Young man recently traveled from Mexico presents with persistent diarrhea with blood and mucus, RUQ pain what does he have

A

Entamoeba histolytic with amebic liver abscess

get stool analysis for cysts of trophozites

32
Q

how will amebic liver abscess present on imaging

A

US: hypoechoic solitary lesion typically in right lobe

33
Q

how to treat intestinal amebiasis

A

if symptomatic use metronidazole then paromomycin

step 2ck (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions