Infections, pathogens and antibiotics Flashcards
Acne
Causative pathogen: propionibacterium acne
Abx: clindamycin or erythromycin (topical)
doxacycline (oral)
Cellulitis
Causative pathogen: strep pyogenes (also staph aureus and MRSA)
Abx: phenoxymethylpenicillin/ flucloxacillin
UTIs
Causative pathogens: klebsiella, E. coli (most common), enterococci, proteus, staph saprophyticus
Abx: Nitrofurantoin/ trimethoprim 3-5 days
Pylonephritis - trimethoprim/ co amoxiclav 7-14 days
Cephalexin instead of trimethoprim in pregnancy
Community acquired pneumonia
CAP: strep pneumoniae, haemophilus influenzae (others: moraxella caterrhalis in immunocompromised, pseudomonas aeruginosa in CF and bronchiectasis, staph aureus in CF)
Abx: CURB-65 score 0-1: amoxicillin/ clarithromycin
2: both
3+: both + co amoxiclav
Atypical CAP
Atypical: legionella pneumoniae, mycoplasma pneumoniae, chlamydia psittaci, coxielia burnetti, chlamydophilia pneumniae
Abx: fluroquinolones e.g. ciprofloxacin / tetracycline
Hospital acquired pneumonia
Pseudomonas aeruginosa, E. coli, klebsiella pseudomoniae
Abx: co amoxiclav, add cefuroxime if severe
TB
Causative pathogen: mycobacterium tuberculosis (others: mycobacterium bovis, africanum and microti)
Treatment: Rifampicin and isoniazid for 6 months, pyrazinamide and ethambutol for 2 months
Sinusitis
Causative pathogen: strep pneumoniae, haemophilus influenzae
Abx: co amoxiclav
Epiglottitis
Causative pathogen: Haemophilis influenzae
Abx: ceftazidime
Whooping cough
Causative pathogen: bordetella pertussis or parapertussis
Abx: clarythromycin (if early stage)
Meningitis
Neisseria meningitidis, strep pneumoniae
In pregnant women: listeria monocytogenes
In children: E coli, strep agalactiae, listeria monocytogenes
In immunocompromised: TB, HIV
Abx: IV cefotaxime/ ceftriaxone
Add IV amoxicillin if age 50+ or immunocompromised
Prophylaxis for contacts - cirpofloxacin
Encephalitis
Most commonly viral - Herpes simplex, varicella zoster, rabies, mumps, coxsackie, japanese, tick-bourne, west nile
Treatment: acyclovir
Shingles
Varicella zoster
Treatment: acyclovir
Exacerbations of COPD
Haemophilis influenzae, strep pneumoniae, moraxella catarhalis
MRSA infection
Abx: vancomycin