Infections of heart Flashcards

1
Q

four stages of infective endocarditis

A
  1. bacterial entry
  2. bacterial adherence to damaged endothelium and microthrombi
  3. bacterial proliferation, neutrophil and macrophage infiltration
  4. vegetation formation
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2
Q

3 eponymous signs of IE

A
  • Osler nodes (painful)
  • Janeway lesions (non painful)
  • Roth spots (retinal haemorrhages with pale centres)
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3
Q

IV drug use endocarditis tends to affect which valve

A

tricuspid

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4
Q

what investigation is key for endocarditis

A

blood cultures

TTE (then TOE)

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