Infections Intro Flashcards

1
Q

What are the 2 types of infections and causes of them

A

Pyogenic- Staph Aureus

Non Pyogenic- TB

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2
Q

What are the tissues that can be involved and names

A

Cellulitis (soft tissues only)
Septic arthritis (joints)
Osteitis (cortical bone)
Osteomyelitis (medullary bone)

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3
Q

4 major pathways of infection spread and MC

A

Hematogenous spread (mc)
Spread from a contigous source
Direct Implantation of infection
post op infection

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4
Q

Infants under 1 vascular anatomy and how it affects infection

A

Metaphyseal vessels can penetrate the growth plate into the joint
-Creates a higher risk of septic arthritis

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5
Q

Between 1 year and skeletal maturatity vascular anatomy and how it affects spread

A

No metaphyseal vessels cross physis (remains as osteomyletitis)

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6
Q

Adult vascular anatomy and how it affects spread

A

Physis no longer present so no barrier to spread; higher incidence of septic arthritis

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7
Q

What is the radiographic latent period for extremities and spine for inf

A

Extremities= 10 days

Spine=21 days

(need mri or bone scan earlier)

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8
Q

what are the earliest signs of osteomyelitis

A

soft tissue changes (seen within 3 days)

  • Will distort fat planes
  • will be hot, red, swollen
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9
Q

What type of bone destruction will you see in infection

A

Early lesion is moth eaten or permiative pattern usually affecting metaphysis- can spread to epiphysis

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10
Q

What type of periosteal rxn may you see in infection

A

Often laminated
codmans triangle
Large involucrum may develop

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11
Q

What is the common age of bone infections and sex predominacne

A

m/c between ages or 2 + 12

3:1 male predominance

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12
Q

IV drug users infection will target these jts usually

A

Spine
SI jt
Symphis pubis
Sternoclavicualr

(mostly axial)

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13
Q

What type of bac are responsible for IV infections

A

Usually gram - bac opposed to staph aureus

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14
Q

Dx criteria of infection

A
  • Red/hot/swollen/tender jts
  • pus on aspiration
  • pos bacterial culture from bone/blood
  • elevated WBC
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15
Q

Diagnostic tests for inf

A

CBC- leukocytosis and anemia in acute (normal chronic)
ESR and C reactive pro usually elevated
Blood culture pos in 50%

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16
Q

Tx for osteomyelitis/septic arthritis

A

Hospital for immediate testing!

  • Supportive tx for pain/fluid intake
  • antibiotic therapy (IV)
  • immobalization
17
Q

Complications of osteomyelitis

A
  • Chronic osteomyletis
  • septic arthritis
  • growth distubrance (especially if young)
  • path fx
  • septicemia
18
Q

Mc organism that causes septic arthritis + area of involvement

A

Staph Aureus

-Hip and Knee (usually monoarticular)

19
Q

Early findings of septic arthritis (x ray)

A
  • Jt effusion
  • soft tissue
  • periarticular osteoperosis
  • loss of jt space
20
Q

Late findings of septc arthritis (x ray)

A
  • AVN/Sequestration
  • marginal and central erosions
  • may progress to bone ankylossi
21
Q

When there is septic arthritis in the spine what is it called

A

Infectious spondylitis

22
Q

Presentation of infectious spondylitis

-when does it develop

A

Disk and adjacent vb destruction (early endplate destruction @ 1 LVL)

  • may see paraspinal/prevert abscess
  • 5/6th decade
23
Q

Where is infectious spondylitis usually

A

90% of skeletal infections involve appendicular skeleton (only 10% in spine)

24
Q

What does infectiohs spondylitis have a high association w

A

UTI