Infections in Pregnancy and the Neonate Flashcards
What is the perinatal period?
22 weeks –> 7 days after birth
What are the complications of congenital rubella syndrome?
Hepatitis-associated jaundice Haemolysis Thrombocytopenia Deafness Cataracts Heart defects
What causes chicken pox?
Varicella Zoster
Describe the symptoms congenital varicella syndrome
Eye defects
Hypoplastic limb
Microcephalus
Describe the symptoms neonatal varicella syndrome
Rash
Pneumonitis
How is varicella syndrome treated?
High dose IV acyclovir
Which pathogen causes slapped cheek syndrome?
Parvovirus
What effects may CMV infection have on foetus?
Deafness
Retardation
What are the consequences of parvovirus?
Foetal anaemia Hydrops fetalis (oedema in foetal compartment)
What happens if you get listeria in early pregnancy?
Foetal death
What are the complications of foetal listeria infection?
Bacteraemia
Hepatosplenomegaly
Meningocephaly
Pneumonitis
What are the consequences of toxoplasma gondii infection in pregnancy?
Stillborn Death soon after birth Cerebral calcification Cerebral palsy Epilepsy
How is toxoplasma gondii transmitted?
Cats are host
Faeco-oral
What increases risk of vertical transmission of HIV?
Advanced maternal disease
High viral load
What pathogen causes syphilis?
Treponema pallidum
