Infections Flashcards

1
Q

What are some presenting features and signs of appendicitis?

A
Generalised abdominal pain that then localises to RIF as peritoneum becomes involved 
Profuse nausea and vomiting 
Anorexia 
Diarrhoea
Guarding 
Rebound tenderness
Fever 
Beware of signs of peritonitis or SHOCK if appendicitis's has ruptured
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2
Q

What would be some differentials for appendicitis?

A

Diverticulitis, Ectopic pregnancy, gastroenteritis, ovarian cyst

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3
Q

What makes appendicitis more difficult to diagnose?

A

Extremes of age and pregnancy

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4
Q

What investigations should you get in appendicitis?

A

FBC, U&E, LFT
- ESR, CRP and WCC will be raised
CT - highly sensitive and specific
USS - very commonly done

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5
Q

How should appendicitis be managed?

A
IV fluids 
Prophylactic Cef and Met 
Contact general surgery 
Slow IV metaclopramide 
Analgesia - opioid
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6
Q

What is cholecystitis?

A

Stones or sludge blocking neck of gall bladder leading to inflammation?
Gall stones is the most important cause

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7
Q

What are some symptoms and clinical signs of cholecystitis?

A

Pain in RUQ, tenderness (Murphy’s sign), Fever, Vomiting, peritonism,
Pain might be referred to right shoulder
Pain might be brought on by eating, particularly something fatty

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8
Q

What are some relevant investigations in cholecystitis?

A

High WCC
USS - thick walls of GB, might see stones, dilated CBD
LFTs - elevation of ALP, bili and ALT - only mild. If very high might suggest full obstruction of bile duct
ALP elevation suggestive of bile duct obstruction

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9
Q

What is the initial management of cholecystitis?

A

Keep them NBM
Give them opioid analgesics
give the IV fluids
Give them IV abx - consult trust guidelines ?Cefuroxime or tazocin
Management is surgical but often not emergency - wait for symptoms to settle

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10
Q

What is cholangitis?

A

This is all the features of cholecystitis PLUS jaundice - INFECTION IN GB.

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11
Q

What are the symptoms of cholangitis?

A

CHARCOT’S TRIAD

  • RUQ pain
  • Jaundice
  • Fevers and Rigors
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12
Q

What increases the risk of cellulitis after a wound?

A
Retention of the foreign body 
Haematoma 
Devitalised tissue 
Poor nutrition and hence decreased immunity 
Diabetes
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13
Q

What is the most common organism to cause cellulitis?

A

Staph Aureus

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14
Q

What is the initial management for cellulitis and when should you consider admission?

A

Consider admission if patient is >38C, systemically unwell, regional lymphadenopathy or cellulitis is widespread
Consider - fluclox, BenPen or co-amox
Monitor vital signs for developing sepsis

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15
Q

What score do we use to grade croup?

A

Westley croup score:
STRIDOR: none=0, when agitated=1, at rest=2
RECESSIONS: mild=1, moderate=2, severe=3
AIR ENTRY: Normal=0, mild decrease=1, marked decrease=2
SpO2<92% on air: Non=0, with agitation=4, at rest=5
Level of consciousness: Normal =0, reduced=5

MODERATE = 3-5, SEVERE 6-11, IMPENDING RESP FAILURE >11

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16
Q

What is the initial management of croup?

A

Oral dexamethasone
Can give inhaled budesonide
adrenaline

17
Q

Describe the scale of features of dehydration

A
MILD
Thirst
Decreased output (<4 wet nappies in 24h)
Dry mouth
MODERATE
Sunken fontanelle
Sunken eyes 
Tachypnoea - due to metabolic acidosis
Tachycardia 
SEVERE
Decreased skin turgor
Drowsiness/irritability
18
Q

What medications can we consider for severe diarrhoea?

A

Anti-emetics might help
ORAL REDHYDRATION: 200-400mL per loose stool
Loperamide

19
Q

What antibiotic/pharmacological therapy should we consider in meningitis?

A

Refer to trust guidelines
Broad spectrum 2nd gen cephs (e.g. ceftriaxone, cefotaxime)
If it is occurring in adult >55 then might consider given AMPICILLIN as well to cover for listeria
Give IV dexamethasone with abx

20
Q

What are some common pathogens that cause otitis media?

A

Streptococcus pneumoniae

Haemophilus influenza

21
Q

How should we manage otitis media?

A
Oral analgesia (PCM)
Might not need antibiotics but if you think they do consider amoxicillin 5 days
22
Q

What is the CURB-65 score?

A
Score used to grade severity of CAP 
Confusion 
Urea >7
Resp rate >30
Blood pressure <90/<60
Age 65

***informs anti-microbial management

23
Q

How should someone with CAP be managed?

A
Oxygen in hypoxic 
Iv fluids if hypotensive 
CXR 
Blood cultures and sputum cultures 
VTE prophylaxis 
Abx according to CURB65
Signs of SIRS (systemic inflammatory response syndrome)
24
Q

How does CURB65 stratification affect antimicrobial management?

A

CURB mild - amoxicillin or clarithromycin
CURB moderate/severe - Amoxicillin/Co-amoxiclav + clarithromcyin (consider IV)

HAP -tazocin

25
Q

What investigations are important to rule out septic arthritis?

A

Joint aspiration
Blood cultures
FBC, U&E

26
Q

How should septic arthritis be managed?

A

IV fluclox + BenPen

Urgent referral to orthopaedics

27
Q

What features within a tonsillitis history will help you decide if it is viral or bacterial?

A

Cough as a predominate symptom makes viral more likely
Exudate +++ on tonsils makes bacterial more likely
High FEVER also makes bacterial more likely

28
Q

What are some common viral causes of tonsillitis?

A

Adenoviruses, EBV, HSV

29
Q

What are some common bacterial causes of tonsillitis?

A

Group A beta-haemolytic strep, mycoplasma, corynebacterium

30
Q

What antibiotic should you definitely not give unless you’ve completely ruled out EBV?

A

Amoxicillin

31
Q

How should you manage a patient with tonsillitis?

A
Recommend PCM cover 1g QDS
Ibuprofen 400mg PO TDS PRN
IF BACTERIAL:
- Penicillin 500mg PO QDS for 5 days OR
- Clarithromycin 500mg PO BD
32
Q

How should you manage an uncomplicated UTI?

A

3-6 day course of Trimethoprim or Nitrofurantoin and advise increased fluid intake
Amoxicillin for treatment of asx bacteriuria
MEN: 2 weeks ciprofloxacin, trimethoprim
CATHETER - 7 days cipro