Infections 9 - HIV Flashcards
What is CD4?
A glycoprotein found on the surface of T cells
HIV enters through CD4
What is viral load?
Quantification of HIV in the blood
What is the natural course of a HIV infection? (6)
Initial increase in viral load (seroconversion illness)
Peak in viral load
Immune system manages
Reduction in viral load but replication is constant
CD4 and T cells decrease
Big viral load increase leading to AIDS
What are the FOUR stages of HIV?
Seroconversion
Asymptomatic
Symptomatic
AIDS
How is HIV diagnosed?
HIV immunoassay test
Name TWO ways of preventing HIV transmission
Condom use
Needle exchange
Name FIVE monitoring requirements for those on ARV treatment
CD4 count Viral load Weight Sexual history Blood pressure
Name TWO side effects of ARV treatment
Headache
Nausea/Vomiting
What are the THREE long term side effects of ARV treatment?
Fat redistribution
Hyperlipidaemia
Hyperglycaemia
What happens if patients do not adhere to treatment?
Drug resistance
Name TWO ways of improving adherance
Individualising therapy to the patient
Reminders
Name THREE counselling points
What the medication is and how it works
Lifelong treatment
Common and important side effects
Name FIVE roles of the pharmacist in HIV treatment
Supply of medication Education Adherence checks Signposting Non-pharmacological advice