Infections Flashcards

1
Q

What are some presenting features and signs of appendicitis?

A
Generalised abdominal pain that then localises to RIF as peritoneum becomes involved 
Profuse nausea and vomiting 
Anorexia 
Diarrhoea
Guarding 
Rebound tenderness
Fever 
Beware of signs of peritonitis or SHOCK if appendicitis's has ruptured
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2
Q

What would be some differentials for appendicitis?

A

Diverticulitis, Ectopic pregnancy, gastroenteritis, ovarian cyst

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3
Q

What makes appendicitis more difficult to diagnose?

A

Extremes of age and pregnancy

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4
Q

What investigations should you get in appendicitis?

A

FBC, U&E, LFT
- ESR, CRP and WCC will be raised
CT - highly sensitive and specific
USS - very commonly done

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5
Q

How should appendicitis be managed?

A
IV fluids 
Prophylactic Cef and Met 
Contact general surgery 
Slow IV metaclopramide 
Analgesia - opioid
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6
Q

What is cholecystitis?

What causes it?

A
  • Inflammation of the gall bladder

- Caused by stones (most commonly) or sludge blocking neck of gall bladder

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7
Q

What are some symptoms and clinical signs of cholecystitis?

A

-RUQ pain
• may be referred to right shoulder
• may be worsened by eating, especially fatty
-Tenderness (murphy’s sign-palpation on inspiration=pain)
-Nausea and vomiting
-Fever
-May get signs of peritonism (guarding, rebound tenderness)
-May be able to feel a mass RUQ (inflamed surrounding bowel)

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8
Q

What are some relevant investigations in cholecystitis and results?

A
Cholecystitis 
Bedside 
-obs and exam 
Bloods
-FBC (high WCC) 
-LFTS (elevation of ALP, bili and ALT - only mild. If very high might suggest full obstruction of bile duct)

Imaging
-USS - thick walls of GB, might see stones, dilated CBD

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9
Q

What is the initial management of cholecystitis?

A

Cholecystitis management
Conservative
-Keep them NBM
-IV fluids

Medical

  • IV opioid analgesics
  • IV Antibiotics (guidelines)

Surgical
-Surgical management (laparoscopic cholecystectomy, normally can wait for symptoms to settle)
(if perf-open surgery)

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10
Q

What is cholangitis?

A
  • Infection of the bile duct

- This is all the features of cholecystitis PLUS jaundice - INFECTION IN GB.

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11
Q

What are the symptoms of cholangitis?

How do you treat this?

A

CHARCOT’S TRIAD

  • RUQ pain
  • Jaundice
  • Fevers/Rigors

Piperacillin and tazobactam

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12
Q

How do you manage cholangitis?

A

Cholangitis managment
-ABCDE management (including blood cultures, IV fluids)

Conservative

  • NBM and NG tube if vomiting
  • Close observation-be aware of sepsis ( to determine the need for emergency decompression of the biliary tree

Medical
-Empirical IV antibiotics depending on blood cultures

Surgical
if medical therapy doesn’t work, they will need surgery (emergency decompression of the biliary tree)

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13
Q

What is the most common organism to cause cellulitis?What increases the risk of cellulitis after a wound?

A

Staph Aureus is the most common cause

Risk factors of cellulitis following a wound:

  • Retention of the foreign body
  • Haematoma
  • Devitalised tissue
  • Poor nutrition and hence decreased immunity
  • Diabetes
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14
Q

What is the initial management for cellulitis and when should you consider admission?

A

Consider admission if patient is >38C, systemically unwell, regional lymphadenopathy or cellulitis is widespread
Consider - fluclox, BenPen or co-amox
Monitor vital signs for developing sepsis

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15
Q

What score do we use to grade croup?

A

Westley croup score:
STRIDOR: none=0, when agitated=1, at rest=2
RECESSIONS: mild=1, moderate=2, severe=3
AIR ENTRY: Normal=0, mild decrease=1, marked decrease=2
SpO2<92% on air: Non=0, with agitation=4, at rest=5
Level of consciousness: Normal =0, reduced=5

MODERATE = 3-5, SEVERE 6-11, IMPENDING RESP FAILURE >11

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16
Q

What is the initial management of croup?

A

Oral dexamethasone
Can give inhaled budesonide
adrenaline

17
Q

Describe the scale of features of dehydration

A
MILD
Thirst
Decreased output (<4 wet nappies in 24h)
Dry mouth
MODERATE
Sunken fontanelle
Sunken eyes 
Tachypnoea - due to metabolic acidosis
Tachycardia 
SEVERE
Decreased skin turgor
Drowsiness/irritability
18
Q

What medications can we consider for severe diarrhoea?

A

Anti-emetics might help
ORAL REDHYDRATION: 200-400mL per loose stool
Loperamide

19
Q

What antibiotic/pharmacological therapy should we consider in meningitis?

A

Refer to trust guidelines
Broad spectrum 2nd gen cephs (e.g. ceftriaxone, cefotaxime)
If it is occurring in adult >55 then might consider given AMPICILLIN as well to cover for listeria
Give IV dexamethasone with abx

20
Q

What investigations are important to rule out septic arthritis?

A

Joint aspiration
Blood cultures
FBC, U+E

21
Q

How should septic arthritis be managed?

A

IV fluclox + BenPen

Urgent referral to orthopaedics

22
Q

What features within a tonsillitis history will help you decide if it is viral or bacterial?

A
Centor criteria
• Tonsillar exudate
• Anterior cervical lymphadenopathy
• Temperature >38
• Absence of cough
If >2 then consider treating with antibiotics

If EBV is suspected then do a monospot test
23
Q

What are some common viral causes of tonsillitis?

A

Adenoviruses, EBV, HSV

24
Q

What are some common bacterial causes of tonsillitis?

A
  • Group A beta-haemolytic strep (strep pyogenes), -mycoplasma
  • corynebacterium
25
Q

What antibiotic should you definitely not give unless you’ve completely ruled out EBV?
How do you rule out EBV?

A

Amoxicillin should not be given unless EBV ruled out with mono-spot test

-It was cause an all over body rash

26
Q

How should you manage a patient with tonsillitis?

Complication of tonsillitis?

A

Paracetamol (1g QDS) and Iboprofun (400mg TDS)
If BACTERIAL:
1. PO phenoxymethylpenicillin 500mg QDS for 5-10 days
2. OR Clarithromycin

Quinsy is a complication which is a peritonsillar abscess

27
Q

How should you manage an uncomplicated UTI?

A

3-6 day course of Trimethoprim or Nitrofurantoin and advise increased fluid intake
Amoxicillin for treatment of asx bacteriuria
MEN: 2 weeks ciprofloxacin, trimethoprim
CATHETER - 7 days cipro

28
Q

What is the aetiology of otitis media?

What are some common pathogens that cause otitis media?

A

-Otitis media is normally a bacterial complication of a viral UTRI
Common pathogens
-Streptococcus pneumoniae
-Haemophilus influenza

29
Q

Presentation of otitis media?

A

Otitis media

  • Earache
  • deafness
  • fever
  • discharge is a later sign associated with a decrease in pain due to perforated tympanic membrane
30
Q

Investigative special test and findings in otitis media?

A

Weber’s test
• Loudest in affected ear(could either be conductive loss in that ear, or sensorineural in other ear)

Rinne’s test
• Test the ear that it localised to
• If Rinnes is abnormal (bone>air) then its condutive hearing loss (seen in otitis media)
• If normal, try other quieter ear (if normal, air>bone) then you know sensorineural loss in that ear

31
Q

How should we manage otitis media?

A

-Oral analgesia (PCM)
-Abx if:
• Perforation
• Bilateral otitis media
• Infants below 2
1st line - amoxicillin

32
Q

What is a complication of otitis media? How should you council patients?

A

Complication: mastoiditis

- look for red boggy swelling behind the ear, pushes the ear forward

33
Q

Compare binary colic, acute cholecystitis and cholangitis?

A

Bilary colic- RUQ (no fever)
Acute cholecystitis-RUQ and fever
Cholangitis- RUQ and Fever AND jaundice