Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Reproductive Pharmacology > Infections > Flashcards

Infections Flashcards

1
Q

Tx for HSV?

A

Acyclovir
Valacyclovir
Famcyclovir/Foscarnet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Tx for Syphilis?

A

Penicillin G

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Tx for Chlamydia?

A 
Azithromycin
Doxycycline
Erythromycin
Levofloxacin/Ofloxain
Amoxicillin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Tx for Chancroid?

A

Azythromycin?Erythromycin
Cerftriaxone
Ciprofloxacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Tx for Gonorhea?

A 
Genital: 
   Cefriaxone
   Axithromycin
   Doxy
   Cefixime
Pharyngeal:
   no cefixime
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Tx for Trichomonas?

A

Metronidazole/Tinidazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Tx for Urethritis?

A 
Acute:
   Azithromycin
   Doxy
   Erythromycine
   Levofloxacin/Ofloxacin
Recurrent:
   Metronidazole/tinidazole
   Azithromycin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Tx for bacterial vaginitis?

A

Type:

fungal: azole
trich: metronidazole
bacterial: clindamycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Tx for candidiasis?

A

Azoles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Tx for HPV?

A 
Gardasil
Cervarix
Podofilox
Imiquimod
Sinecatechins
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Acyclovir MOA/AE?

A

Guanasine analog
Competes for deoxyGTP
Inhibits viral DNA polymerase
Needs TK activation: adds 1st of 3 phosphates

AE:
Renal crystaliasis
Neurotoxic: seizures
Cross reactivity HS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Famcyclovir MOA/AE?

A

Not TK needed
guanosine analog like acyclovir

AE;
second line
no neurotoxicity
liver metabolism to penciclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Penicillin MOA/AE?

A

PBP

HS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Azithromycin MOA/AE?

A

MOA: static
50s ribosomal subunit
prevent peptidyl-transferase from adding AA

AE:
inactivated by gastric acid
GI upset
vaginitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Doxycycoline MOA/AE?

A

MOA: static
30S

AE:
    cat D drug: not in pregnancy (teeth!)
    GI
    Hepatic damage in pregnancy
    Photosensitivity
    Discoloration
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Levofloxacin MOA/AE?

A

MOA: cidal
G- block DNA gyrase
G+ block topo4

AE: 
     Taste disturbance
     GI
     BBW: tendon rupture
     muscle weakness: avoid in myasthenia gravis
     Cat C: animal studies
17
Q

Ceftriaxone MOA/AE?

A

MOA: cidal
PBP: fancy beta lactam: lysis

AE:
     Does not cross placenta
     Breastfed baby has diarrhea: breast milk
     candidiasis
     rash
18
Q

Metronidazole MOA/AE?

A

MOA: cidal for everything
disrupts DNA helix after uptake into bugs
dividing and non dividing cells effected

AE: 
   Avoid in pregnancy/breastfeeding (DNA!!)
    *Disulfiram: alcohol makes nausea!
    *Secondary malignancy
    GI
    Candidiasis
19
Q

Clindamycin MOA/AE?

A

MOA: static
50S

AE: intravaginal only!
     1st trimester only: 
           low weight
           pre term
           PROM-->neonatal infections
    Breast milk excretion
     GI upset
    contact dermatitis
20
Q

Azoles MOA/AE?

A

MOA:
14alpha demethylase CYP
prevent lanosterol to ergosterol synthesis

AE:
    Cat X: cleft palate, abdominal wall
     maternal stress (avoid 1st trimester)
     Break condoms/diaphragms
21
Q

Gardasil coverage?

A

6,11,16,18: warts and cancer

22
Q

Cervarix coverage?

A

16,18: cancer only (Cervarix=C=Cancer only)

Reproductive Pharmacology (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions