Infection Processes Flashcards
Infection
Invasion/colonization of body by pathogenic microorganisms
Disease
Occurs when infection results in change from normal state of health
Pathogen
Microorganism/virus able to produce disease
Location of portal exit
Usually close to organism’s breeding site
Transmission of disease pathway
(1) Reservoir
(2) Portal of exit
(3) Mode of transmission
(4) Portal of entry
(5) Susceptible victim
Factors for infection
(1) Communicability
(2) Immunogenicity
(3) Pathogenicity
(4) Toxingenicity
(5) Virulence
Risk factors for susceptibility
- nutritional status
- chronic illness
- age
- immunosuppression
- environment
- HAI
Breaking the chain of infection
- destroy reservoir
- block portal of exit/entry
- block mode of transmission
- reduce victim’s susceptibility/improve immune system
- use antimicrobials with caution
Stages of infection
(1) incubation period
(2) prodromal stage
(3) invasion/acute illness
(4) convalescence
Classes of infectious microorganisms
- bacteria
- fungi
- protozoa
- virus
- helminths
Symbiosis
benefits only the host not the organism
Mutualism
benefits host and microorganism
Commensalism
benefits only the microorganism, no harm to host
Pathogenicity
benefits the microorganism, harms the host
Opportunism
Benign microorganisms become pathogenic due to decreased host resistance or translocation to other body sites