Infection

Question 1

What do neutrophils fight?

Answer 1

Bacteria and fungi

Question 2

What do monocytes fight?

Answer 2

Fungal infections

Question 3

What do eosinophils fight?

Answer 3

Parasitic infections

Question 4

What do T lymphocytes fight?

Answer 4

Fungal and viral infections, PJP

Question 5

What do B lymphocytes fight?

Answer 5

Bacterial infections

Question 6

What supportive measures are aimed at reducing risk of sepsis in haematological malignancy?

Answer 6

Prophylaxis (antibiotics, e.g. ciprofloxacin, antifungals, e.g. fluconazole), anti-virals (e.g. acyclovir), PJP (e.g. co-trimoxazole)
Growth factors, e.g. CG-CSF
Stem cell rescue/Tx
Protective environment, e.g. laminar flow rooms
IVIg
Vaccination

Question 7

True or False

Marrow failure has a higher risk of neutropenia that immune destruction

Answer 7

True

Question 8

What degree of neutropenia would indicate a significant risk?

Answer 8

<0.5x10^9

Question 9

What degree of neutropenia would indicate a high risk?

Answer 9

<0.2x10^9

Question 10

What duration of neutropenia would indicate a high risk?

Answer 10

7 days