Ineffective Tissue Perfusion (blood) Flashcards
What cell types does blood consist of?
erythrocytes (rbc), leukocytes (wbc) and thrombocytes (platelets)
What makes up the largest portion of blood?
plasma (55%)
What percentage is the cellular component of blood volume?
40-45%
What are the two types of stem cells resulting from bone marrow
myeloid and lymphoid
What does plasma contain
albumin and globulin
Is liver function is decreased what does that mean for albumin and edema?
decreased albumin and increased edema
What does hematopoiesis mean?
replenishment of blood
Where does primary hematopoiesis occur?
Bone marrow (pelvis, ribs, vertebrae, and sternum)
Where does hematopoiesis occur is bone marrow is suppressed?
In the liver or spleen (extramedullary hematopoiesis)
What does hemostasis mean?
Leaks are sealed off which creates a balance between clotting and dissolving clots
What are the steps for clotting
- cut occurs
- blood vessels constrict
- platelets rush to site, stick to site and each other
- circulating coagulation factors activate
- Fibrin reinforces, protects, and anchors sheath.
What are diagnostic test used to assess hematologic disorders?
CBC, blood smear, PTT, PTINR, bone marrow biopsy
What’s the difference between PTT and PTINR
PTT is clotting time with reagents, PTINR is clotting time without reagents
What is the antidote for warfarin
vitamin K
If your patient is on coumadin, what can you expect their PT INR to be?
2-3 times higher than normal
What is important information for patient’s to know prior to getting a bone marrow biopsy
No aspirin or Advil 24-48 hours prior
Bone marrow aspiration occurs where?
sternum
bone marrow biopsy occurs where?
anterior iliac crest
If someone is anemic what will you notice about their tongue?
beefy red tongue
What does reticulocyte count indicate?
The number of baby blood cells
how do you diagnose anemias
H/H, reticulocyte count, RBC indices, Iron level, Vitamin B12 level, stool occult blood, bone marrow aspiration, and if hemorrhaging dx site
What does lysis mean?
destruction of
what does penia mean
too few
What does hypo-proliferative mean and examples within anemia
not making or keeping enough
1. iron deficiency anemia
2. aplastic anemia
3. vitamin B deficiency anemia