Indications Flashcards
What conditions indicate topical antibiotic meds?
superficial skin infections and ocular surface disease: bacterial conjunctivitis, bacterial keratitis, blepharitis, external hordeola
What conditions indicate prophylactic infection treatment with antibiotics?
pre-op and post-op, corneal abrasion, recurrent corneal erosion, conjunctival abrasion +FBS
What conditions indicate oral antibiotics?
skin and soft tissue infection: internal hordeola, pre-septal cellulitis, dacryoadenitis, dacryocystitis
What conditions indicate injectable antibiotics?
intraocular and intraorbital infections: endophthalmitis, orbital cellulitis
What medication is indicated if you need gram (+) coverage peptidoglycan cell wall inhibitor?
bacitracin (in ointment form only, because in solution, it is replaced by gramicidin)
What medication is indicated if you need gram (+) coverage and MRSA coverage peptidoglycan cell wall inhibitor?
vancomycin
When would a compounded ophthalmic vancomycin be indicated?
when other antibiotics are not effective, especially with corneal ulcer
T/F MRSA is resistant to all b-lactam antibiotics
true
What drug is indicated for gram (+) and some (-) in the penicillin group?
aminopenicillins: amoxicillin and augmentin
What coverage does augmentin have?
gram (+) limited (-) and Haemophilus
Which cephalosporins have the best gram (+) coverage with some (-)?
cefazolin and cephalexin (Keflex)
Which cephalosporins have improved gram (-) and decreased gram (+)?
cefaclor
Which cephalosporin is good for children?
cefaclor
Which cephalosporins have FURTHER improved gram (-) and decreased gram (+)?
cefdinir, ceftriaxone, ceftazidime
Which cephalosporin is indicated for gonorrhea?
ceftriaxone (IM)
Which cephalosporin is indicated for orbital cellulitis?
ceftriaxone (IV)
What coverage do aminoglycosides have?
gram (-) including pseudomonas; topicals have some gram (+)
What coverage does tobramycin have that the other aminoglycosides do not?
MRSA
Rank to aminoglycosides according to pseudomonas coverage
tobramycin>gentamicin>neomycin
Which aminoglycosides can be fortified for corneal ulcer?
gentamicin and tobramycin
Which aminoglycoside is broad spectrum but has holes against pseudomonas and streptococcus?
neomycin
What coverage do tetracyclines have?
gram (+) and (-) including MRSA
What drug is indicated for lyme disease?
tetracycline
What are the two DOC for inclusion conjunctivitis?
doxycycline AND azithromycin
What are the five drugs indicated for inclusion conjunctivitis?
doxycycline, erythromycin, azithromycin, ofloxacin, levofloxacin
Which drug is indicated for rosacea and blepharitis?
doxycycline
What are two off-label uses of doxycycline?
pterygium and RCE
Which macrolide is narrow spectrum?
erythromycin
What is erythromycin ointment used for?
ocular surface infection and prophylaxis of ophthalmic neonatorum
What coverage does azithromycin have?
gram (-), (+) and chlamydia
What is the ophthalmic solution of azithromycin indicated for?
gram (+) and haemophilus, bacterial conjunctivits