Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Pharm II Exam 2 > Indications > Flashcards

Indications Flashcards

1
Q

L-triiodothyronine (T3)

Liothyronine Sodium

A

Not used much

Shorter HL because T3 so must be given multiple times a day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

L-thyroxin (T4)

Levothyroid Sodium

A

Drug of choice for hypothyroidism

1x daily

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Liotrix

T4:T3 at 4:1

A

Not usually necessary because body converts T4 to T3 (may be good if polymorphism in deiodinase enzyme)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Thioamides - PTU and MMI

A

Mild -Moderate hyperthyroidism

Tx for preop thyroidectomy for ~6 wk until euthyroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Propylthiouracil

PTU

A

Thyroid storm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Anion Inhibitors- (ClO4-) and (TeO4-)

A

Block thyroidal uptake of iodide in patients with iodide induced hyperthyroidism
(such as amiodarone induced hyperthyroidism)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Iodide

A

Hyperthyroidism rarely used (thioamides are better)

Can use in combo with PTU and B-blocker in thyroid storm (acute thyroid crisis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Radioactive Iodine

I131

A

Thyrotoxicosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

First line tx for DM2

A

exercise & weight control

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Metformin

A

First line med for type 2 diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Glipizide

A

DM2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Repaglinide

A

DM2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Pioglitazone

A

DM2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Exenatide

A

DM2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Sitagliptin

A

DM2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Acarbose

A

DM2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Canagliflozin

A

DM2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are agonist uses of Estrogens and Progestins?

A

Menopausal hormone therapy

Contraception

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are antagonist uses of Estrogens and Progestins?

A

Hormone-responsive breast cancer therapy

Emergency contraception, medical abortion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Estrogens

A

Contraceptive (not used as single agent)

Estrogen deficiency

Hirsuitism, amenorrhea, dysfunctional uterine bleeding, dysmenorrhea

21
Q

Progestins

A

Contraception

22
Q

Levonorgest

A

Emergency Contraceptive within first 120 hrs post-unprotected sex

23
Q

Norethindrone

A

contraception

24
Q

Progesterone

A

contraception

25
Progestin only pill
contraception
26
Estrogen/Progestin Combo Pill
Contraception
27
Ulipristal
Emergency Contraceptive within first 120 hrs post-unprotected sex Uterine fibroids
28
Mifepristone | RU486
Termination of early pregnancies along with PGE1(misoprostal) Emergency contraception (not drug of choice)
29
Tamoxifen
Treat early stage or metastatic ER+ breast cancer in pre- or post- menopausal patients ↓ risk of cancer development Note that ER+/PR+/HER2- pts respond best to SERMs
30
Toremifene
Treat metastatic ER+ breast cancer in post- menopausal patients
31
Leuprolide
Treat metastatic or early stage ER+ breast cancer in pre- menopausal patients May be combined with SERMs Note: ASCO does not consider this to be best treatment option for early stage breast cancer → consider tamoxifen
32
Aromatase Inhibitors
Treat early stage or metastatic ER+ breast cancer in post- menopausal patients More effective than tamoxifen (greater survival) in post- menopausal patients
33
Trastuzumab
Metastatic HER2+ breast cancer resistant to trastuzumab and/or taxanes
34
Pertuzumab
Metastatic HER2+ breast cancer; used in conjunction with trastuzumab and docetaxel
35
Cyclophosphamide
Lymphomas Leukemias MM Breast and ovarian ca Small cell lung cancer Some autoimmune conditions
36
Cisplatin
Testicular/Ovarian ca Bladder ca Small and non-small cell lung ca Colon ca
37
Carmustine (bi-fn) Lomustine and Semustine (mono-fn)
Brain tumors
38
Streptozocin
Insulin-secreting islets carcinoma cells
39
Methotrexate
Breast ca Head & Neck ca Bladder ca Lung carcinomas Lymphomas ALL
40
5-Fluorouracil
Colon ca Breast ca Gastroesophageal ca Hepatocellular ca Pancreatic carcinomas
41
6-Mercaptopurine
ALL and AML Crohn's
42
Vinblastine
Breast cancer Hodgkin’s and non-Hodgkin’s lymphoma
43
Vincristine
Childhood | leukemias and cancers
44
Paclitaxel
Ovarian, breast, bladder,ca Non-small cell lung cancers
45
Etoposide
Testicular ca Non-small cell and small cell lung ca AML and ALL Hodgkin’s and non-Hodgkin’s lymphoma
46
Irinotecan
Metastatic | colon cancer
47
Doxorubicin
Hodgkin’s and non-Hodgkin’s Breast, ovarian and bladder ca ALL NOT good for solid tumors
48
Bleomycin
Testicular carcinoma SCC Hodgkin’s and non-Hodgkin’s lymphomas
49
What drug can you use to prevent hyperuricemia during 6-MP tx of leukemias?
Allopurinol

Pharm II Exam 2 (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions