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pharm quiz 5 > Incretins > Flashcards

Incretins Flashcards

1
Q

2 Classes?

A

GLP 1 Agonists - FROM DRAGONS

DPP IV Inhibitors

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2
Q

Name 3 GLP 1 Agonists

A

Liraglutide
Albiglutide
Dulaglutide

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3
Q

Basic MOA GLP 1 Agonists

A

Binds / Activates GLP 1 receptor&raquo_space; increase insulin secretion, decrease hepatic glucose output

**slows rate of gastric emptying, reduces food intake, increases satiety **

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4
Q

GLP 1 Advantages

A

Decreases BP
Decreases TG, CRP, BNP
Improves endothelial function

**weight loss, 84 % patients **

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5
Q

GLP 1 ADRs

A

GI N/V/D - usually decreases w time

Injection site irritation
Antibody formation
Possible pancreatitis

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6
Q

GLP 1 Contraindications

A

Gastroparesis may decrease absorption rate of other meds
Pancreatitis
Renal Insufficiency

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7
Q

Which GLP 1 was approved for weight loss but has a black box warning for Thyroid C cell Tumors?

A

Liraglutide (“Saxenda’ for weightless)

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8
Q

Name 4 DPP-4 Inhibitors GLIPTINS

SITASAXALOGIN

A

Lina
Alog
Sita
Saxa

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pharm quiz 5 (4 decks)

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