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IMMUNOSERO > IMSE QUIZ 1 > Flashcards

IMSE QUIZ 1 Flashcards

1
Q

From the following, identify a specific component of the adaptive immune system that is formed in response to antigenic stimulation:

A. Lysozyme
B. Complement
C. Commensal organisms
D. Immunoglobulin

A

Immunoglobulin

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2
Q

Which T cell expresses the CD8 marker and acts specifically to kill tumors or virally infected cells?

A. Helper T
B. T suppressor
C. T cytotoxic
D. T inducer/suppressor

A

T cytotoxic

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3
Q

What is the name of the process by which phagocytic cells are attracted to a substance such as a bacterial peptide?

A. Diapedesis
B. Degranulation
C. Chemotaxis
D. Phagotaxis

A

Chemotaxis

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4
Q

Which of the following cell surface molecules is classified as an MHC class II antigen?

A. HLA-A
B. HLA-B
C. HLA-C
D. HLA-DR

A

HLA-DR

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5
Q

Which MHC class of molecule is necessary for antigen recognition by CD4-positive T cells?

A. Class I
B. Class II
C. Class III
D. No MHC molecule is necessary for antigen

A

Class II

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6
Q

Which of the following are products of HLA class III genes?

A. T-cell immune receptors
B. HLA-D antigens on immune cells
C. Complement proteins C2, C4, and Factor B
D. Immunoglobulin VL regions

A

Complement proteins C2, C4, and Factor B

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7
Q

What molecule on the surface of most T cells recognizes antigen?

A. IgT, a four-chain molecule that includes the tau heavy chain
B. MHC protein, a two-chain molecule encoded by the HLA region
C. CD3, consisting of six different chains
D. TcR, consisting of two chains, alpha and beta

A

TcR, consisting of two chains, alpha and beta

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8
Q

Toll-like receptors are found on which cells?

A. T cells
B. Dendritic cells
C. B cells
D. Large granular lymphocytes

A

Dendritic cells

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9
Q

Macrophages produce which of the following proteins during antigen processing?

A. IL-1 and IL-6
B. γ-Interferon
C. IL-4, IL-5, and IL-10
D. Complement components C1 and C3

A

IL-1 and IL-6

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10
Q

A superantigen, such as toxic shock syndrome toxin-1 (TSST-1), bypasses the normal antigen processing stage by binding to and cross linking:

A. A portion of an immunoglobulin molecule and complement component C1
B. Toll-like receptors and an MHC class 1 molecule
C. A portion of an immunoglobulin and a portion of a T-cell receptor
D. A portion of a T-cell receptor and an MHC class II molecule

A

A portion of a T-cell receptor and an MHC class II molecule

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11
Q

Enhancement of phagocytosis by coating of foreign particles with serum proteins is called?

A. Opsonization
B. Solubilization
C. Agglutination
D. Chemotaxis

A

Opsonization

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12
Q

Jenner’s work with cowpox, which provided immunity against smallpox, demonstrates which phenomenon?

A. Natural immunity
B. Attenuation of vaccines
C. Phagocytosis
D. Cross-immunity

A

Cross-immunity

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13
Q

Which of the ff. can be attributed to Pasteur?

A. Discovery of opsonins
B. Research of haptens
C. First attenuated vaccines
D. Discovery of the ABO blood groups

A

First attenuated vaccines

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14
Q

Which of the following peripheral blood cells plays a key role in killing of parasites?

A. Neutrophils
B. Lymphocytes
C. monocytes
D. eosinophils

A

eosinophils

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15
Q

Which of the ff. plays an important role as an external defense mechanism?

A. Phagocytosis
B. Lysozyme
C. CRP
D. Complement

A

Lysozyme

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16
Q

The process of inflammation is characterized by all of the ff. except?

A. Increased blood supply to the area
B. Migration of WBCs
C. Decreased capillary permeability
D. Appearance of acute phase reactants

A

Decreased capillary permeability

17
Q

Skin, lactic acid secretions, stomach acidity and the motion of cilia represent which type of immunity

A. Natural
B. Adaptive
C. Acquired
D. AOTA

18
Q

The structure formed by the fusion of engulfed material and enzymatic granules within the phagocytic cells is called

A. Phagosome
B. Vacuole
C. Lysosome
D. Phagolysosome

A

Phagolysosome

19
Q

Which of the ff. WBCs is capable of further differentiation in the tissues?

A. Neutrophil
B. Basophil
C. Eosinophil
D. Monocyte

20
Q

The presence of normal flora acts as a defense mechanism by which of the ff means?

A. Maintaining an acid environment
B. Competing with pathogens for nutrients
C. Keeping phagocytes in the area
D. Coating mucosal surfaces

A

Competing with pathogens for nutrients

21
Q

Measurement of CRP levels can be used for all of the ff. except?

A. Monitoring drug therapy with anti-inflammatory agents
B. Tracking the normal progress of surgery
C. Diagnosis of a specific bacterial infection
D. Determining active phase of RA

A

Diagnosis of a specific bacterial infection

22
Q

Which of the ff. are characteristics of APRs?

A. Rapid increased following infection
B. Enhancement of phagocytosis
C. Nonspecific indicators of inflammation
D. AOTA

23
Q

A latex agglutination test for CRP is run on a 12 year old girl who has been ill for the past 5 days with an undiagnosed disease. The result obtained are as follows: weakly reactive with the undiluted serum and negative for both the positive and negative controls. What should the medical technologist do next?

A. Repeat the entire test
B. Report the results as indeterminate
C. Report the result as positive
D. Obtain a new sample

A

Repeat the entire test

24
Q

Which is the most significant agent formed in the phagolysosome for the killing of microorganisms?

A. Proteolytic enzymes
B. Hydroxyl radicals
C. Hydrogen peroxide
D. Superoxides

A

Hydrogen peroxide

25
Q

The action of CRP can be distinguished from that of an antibody in which of the ff ways?

A. CRP acts before the Ab appears
B. Only the Ab triggers the complement cascade
C. Binding of the antibody is calcium-dependent
D. Only CRP acts as an opsonin

A

CRP acts before the Ab appears

26
Q

The first line of defense in protecting the body from infection includes all the following components except:

a. Unbroken skin
b. Normal microbial flora
c. Phagocytic leukocytes
d. Secretions such as mucus

A

Phagocytic leukocytes

27
Q

Natural immunity is characterized as being:

a. Innate or inborn
b. Able to recognize exogenous or endogenous agents specifically
c. Able to eliminate exogenous or endogenous agents selectively
d. Part of the first line of body defenses against microbial organisms

A

Innate or inborn

28
Q

Another term for adaptive immunity is:

a. Antigenic immunity
b. Acquired immunity
c. Lymphocyte reactive immunity
d. Phagocytosis

A

Acquired immunity

29
Q

Humoral components of the adaptive immune system include:

a. T lymphocytes
b. B lymphocytes
c. Antibodies
d. Saliva

A

Antibodies

30
Q

Which of the following characteristics of an antigen is the least important?

a. Foreignness
b. Degradability
c. Molecular weight
d. Presence of large repeating polymers

A

Presence of large repeating polymers

IMMUNOSERO (12 decks)

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