Impulse, Eating, Sleep/wake Flashcards
Intermittent explosive disorder
Verbal/physical outbursts: 2x/week, for 3+ months
OR
Outbursts resulting in physical damage, 3+ times/year
- Not premeditated
- Out of proportion reaction to stressor
- Cause impairment or distress
Mgmt:
- SSRI (fluoxetine), mood stabilizers (anticonvulsants, lithium)
- CBT
- Group/family therapy
Kleptomania
F > M
Uncontrollable urges to steal unnecessary objects
Increasing tension right before theft
*Strongly assoc with bulimia nervosa, OCD
Mgmt:
- SSRI’s
- CBT
- Naltrexone use (may help?)
Pyromania
At least 2 epi’s of fire setting
- Highly comorbid with mood/substance disorders, gambling, conduct disorder
- Episodic epi’s that wax, wane
Mgmt:
Not really anything … CBT, SSRI, mood stab
What are the 2 types of anorexia nervosa?
- Restricting type
Has not regularly engaged in binge-eating or purging; wt loss from dieting, exercise, and/or fasting - Binge-eating/purging type
Binges —> purging (laxatives, self induced vomiting)
Sometimes will purge w/o binging
Anorexia vs. bulimia, MDD
Anorexia: low body wt + restriction of calorie intake
Bulimia: nml or over- wt; sx usually more ego-dystonic, more likely to seek help
Anorexia vs MDD:
Anorexics have a good appetite
Physical sx of anorexia
Amenorrhea Cold intolerance/hypothermia Hypotension (esp orthostasis) MVP Constipation Lanugo Alopecia Edema Dehydration Peripheral neuropathy Seizures Hypothyroidism Osteopenia Osteoporosis
Lab/imaging abn of anorexia
Enlg’ed ventricles
Decrease in gray and white matter
Peripheral neuropathy
Decreased Na, Cl, K (alkalosis if vomiting) Arrhythmia (esp QTc pr) Hypercholesterolemia Transaminitis Normocytic, normochromic aemia High BUN High GH, cortisol Low LH, FSH, sex steroid hormones (estrogen, T), glu
Tell me about anorexia!
Assoc with 3 things
Mgmt
- Assoc with OC personality traits
- Bimodal onset (13-14, 17-18 yo)
- Difficulty with separation, autonomy, struggle to gain control
Mgmt:
- CBT
- Family therapy (Maudsley)
- Supervised wt gain program
** If no improvement with standard therapy, can consider adding –> olanzapine (antipsychotic)
F/u: Refeeding syndrome
Fluid retention + low Ph, Mg, Ca
+/- resp failure, delirium, seizures, arrhythmias
(tx: replace lytes, slow feeding)
How do you dx and manage bulimia?
Binge eating: excessive food intake within 2 hrs (accompanied by lack of control)
Compensatory behaviors: vomiting, diuretics, laxatives
1+/week, duration: 3+ months
Mgmt:
1. SSRI (fluoxetine) + therapy COMBO (CBT, fam therapy, etc)
** AVOID BUPROPION **
Binge eating disorder
Dx
Mgmt
Not fixated on body wt and shape
Binges, assoc with distress
1+/week, duration: 3+ months
Usually obese
Mgmt:
- Individual psychotherapy; strict diet + exercise
- Possibly drugs for wt loss:
- Stimulants (phentermine, etc) - suppress appetite
- Topiramate, zonisimide - wt loss
- Orlistat - don’t absorb fat
What characterizes REM sleep?
Increase in
- BP
- HR
- RR
Dyssomnias
(insomnia or hypersomnia)
Dx
Mgmt
3+/week, duration: 3+ months
*Not adequately explained by comorbid moods disorders
Acute: <3 months
Chronic: 3+ months
Mgmt:
- CBT (first line for chronic insomnia)
- Sleep hygiene
- Meds:
- BZ’s (short term; falls in elderly; addiction)
- Non-BZ’s (zolpidem causes more falls in elderly, and cognitive impairment in women at high doses)
- Antidepressants - trazodone
Hypersomnolence disorder (M = F)
Dx
Etiology
Mgmt
Criteria: excessive sleepiness despite 7 hrs, with:
- recurrent pds of sleep
- prolonged nonrestorative sleep >9 hr
- difficulty being fully awake after awakening
3+/week, duration: 3+ months
Etio:
- Viral infections
- Head trauma
- Genetic (AD)
Mgmt:
1. Lifelong tx with modafinil or stimulants (methylphenidate)
(second line = atomoxetine)
2. Scheduled napping
Obstructive sleep apnea / hypopnea (M > F)
Repetitive collapse of upper airway
Polysomnography: apneic / hypopneic episodes (>15/hr)
- Excessive daytime sleepiness
- Sleep fragmentation
- Snoring
- Morning HA’s
- HTN
Mgmt:
- CPAP … or BiPAP
- Wt loss, exercise
- Surgery
Central sleep apnea
5+ central apneas/hour of sleep
(cessation of both airflow and ventilatory effort)
insomnia, daytime sleepiness
Etio:
- PRIMARY: idiopathic
- SECONDARY:
- Cheyne-Stokes breathing - sec to HF, stroke, renal failure)
- Opioid use
Mgmt:
- Treat underlying condition
- CPAP/BiPAP
- Supplemental O2
- Meds (acetazolamide, theophylline (stimulates breathing), sedative-hypnotics)