Important parameters in Physiology: CELLULAR

Question 1

Body water content

(assume individual weighing 70kg)

Answer 1

Total Body Weight (TBW)= (o.6x body weight)=42L

ECF=(0.2xbody weight)=14L

• interstial fluid (3/4= 14L)
• plasma ECF (1/4=3.5L)

ICF=(0.4xbody weight)=28L

Question 2

blood volume

Answer 2

blood volume as part of ECF is determined by sodium balance or total sodium in body

Question 3

Plasma Volume

Question 4

ECF fluid volume

Question 5

intracellular fluid volume

Question 6

interstiatial fluid volume

Question 7

hematocrit

Question 8

Hb concentration

Question 9

Blood plasma concentration: Na+

Answer 9

135-147mM

Question 10

Blood plasma concentration K+

Answer 10

3.5-5.0 mM

Question 11

Blood plasma concentration Ca2+

Answer 11

2. 1-2.8mM (total)
3. 1-1.4 mM (free)

Question 12

Blood plasma concentration Cl-

Answer 12

95-105 mM

Question 13

Blood plasma concentration HCO3-

Answer 13

22-28mM

Question 14

Blood plasma protein concentration

Question 15

Intracellular concentration Na+

Answer 15

10-15 mM

Question 16

Intracellular concentration K+

Answer 16

120-150mM

Question 17

Intracellular concentration ca2+

Answer 17

100 nM (free)

Question 18

Intracellular concentration Cl-

Answer 18

20-30 mM

Question 19

Intracellular concentration HCO3-

Answer 19

12-16 mM

Question 20

Intracellular osmolality

Answer 20

290 mOsm

Question 21

intracellular PH

Answer 21

7.2

Question 22

ionic composition of ECF and iCF

Answer 22