important facts

Question 1

drug induced lupus erythematosus

Answer 1

Procainamide, hydralazine, Isoniazid

Question 2

drug of choice for ventricular dysrhythmias

Answer 2

Amiodarone (class III), old DOC lidocaine

Question 3

which class of drugs is not suitable for treatment of variant angina? (vasospasms)

Answer 3

All beta-blockers are ineffective against variant (vasospastic) angina. Nitrates and calcium blockers are effective.

Question 4

SE of nitrates

Answer 4

reflex tachy cardia

Question 5

if a patient has had a myocardial infarction and needs prophylactic antiarrhythmic pharmacotherapy, what medication should they be given?

Answer 5

metoprolol (beta blocker?)

Question 6

Useful for suppressing the activity of the SA node, may cause depression and sleep disturbances.

Answer 6

metoprolol

Question 7

which agents can cause the greatest decrease in triglyceride levels?

Answer 7

the fibrates ( Gemfibrozil)

Question 8

____ is a CYP3A4 substrate and inhibitor and thus may enhance the effect of other CYP3A4 substrates eg. Warfarin, Simvastatin, Verapamil

Answer 8

amiodarone