Important course concepts Flashcards
Controlled Substances Act of 1970
First measure to control drug use.
Created “schedule” system, rated based on abuse potential and medical use.
Schedule 1
high abuse potential, no accepted medical use.
Examples: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote
Schedule 2
High abuse potential, psychological or physiological dependence liability, medically used
Examples: Combination products with less than 15 milligrams of hydrocodone per dosage unit (Vicodin), cocaine, methamphetamine, methadone, hydromorphone (Dilaudid), meperidine (Demerol), oxycodone (OxyContin), fentanyl, Dexedrine, Adderall, and Ritalin
Schedule 3
Some abuse potential
Examples: Products containing less than 90 milligrams of codeine per dosage unit (Tylenol with codeine), ketamine, anabolic steroids, testosterone
Schedule 4
Less abuse potential
Examples: Xanax, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Tramadol
Schedule 5
Least abuse potential, over the counter drugs
Dispositional tolerance
The body speeds up the metabolism of a drug to eliminate it by up-regulating enzyme production
Pharmacodynamic tolerance
Down regulation of receptors.
Nerve cells become less sensitive to the effect of a drug. Body can also produce antagonist to the drug. For example: use of opioids causes the brain to make fewer opioid receptor sites
Behavioral tolerance
The brain learns to compensate for the effects of the drug by using unaffected parts. “overriding” the effects of the drug with will power.
Reverse tolerance
In response to destruction of tissues from prolonged use, the user becomes more sensitive and less able to handle moderate amounts of the substance.
Acute tolerance (tachyphylaxis)
Brain and body begin to adapt instantly in response to initial use of a substance.
Select tolerance
Body develops tolerance to mental and physical effects at different rates. Dose to reach emotion high is not the same as the physical level of tolerance.
Inverse tolerance (kindling)
A person becomes more sensitive to the effects of a drug as the brain chemistry and neuron pathways adapt to the drug’s effects.
Cross tolerance
Developing tolerance to one drug increases tolerance to other drugs with similar biological pathways as well
Non-purposive withdrawal
Characterized by objective physical signs that are a direct result of developing tissue dependence
Purposive withdrawal
A false portrayal of severe withdrawal symptoms by an addict to gain drugs from prescribers.
Can also be caused by psychic conversion reaction: emotional expectation of physical effects.
Protracted withdrawal
Flashback or recurrence of the addiction withdrawal symptoms triggers heavy craving even after detox is complete. Caused by environmental triggers.
“Levels of use” progression
Abstinence, initial contact, experimentation, social/recreational, habituation (integrated use), abuse (excessive use), addiction
Stages of recovery
Withdrawal, honeymoon, the Wall, adjustment, resolution
Withdrawal
0-15 days after use
Low energy, need more sleep
Difficulty concentrating, cravings, short term memory problems
Hostility, confusion, fear, depression, doubt, shame
Honeymoon
16-45 days after use
High energy, poorly directed behavior, secondary drug use
Shorter attention span, denial about relapse potential
Optimistic and overly confident
Desire to return to “normal” may cause conflicts with family members
The Wall
46-120 days after use
Low energy, apathetic, sleep disturbances, discontinuation of recovery behaviors
Romancing use, rehearsal of relapse, increased cravings
Anxiety, depression, fatigue, boredom, irritability, anhedonia
Blaming, devaluation of progress
Adjustment
121-180 days after use
Return to risky situations, decrease in recovery /abstinence promoting behaviors
reduced thoughts of use and cravings
reduced depression, anxiety and irritability but continued boredom and loneliness
Resistance to assistance with relationship problems
Resolution
181+ days after use
Emergence of other excessive use behaviors
Questions need for long term support
Emergence of emotional material, boredom with abstinence
Pre-treatment stages
Denial, ambivalence, motivation (extrinsic), motivation (intrinsic) readiness for change, readiness for treatment
Treatment-related stages
De-addiction, abstinence, continuance, integration and identity change
Recovery model
Self-directed, individualized, person-centered, empowerment oriented, holistic, non-linear, strengths-based, peer supported, respectful, emphasizes personal responsibility, and fosters hope.