Important Clinical Manifestations and Fever Flashcards
What is the clinical criteria for sepsis Determination and other risk factors
qSOFA:
- Respiratory rate greater than 22
- Altered mentation
- Systolic blood pressure less than 100
Other:
- ICU admission
- Bacteremia
- Age greater than or equal to 65
- Immunosuppression
- Diabetes and obesity
- Cancer
- Community acquired pneumonia
- Previosu Hospitalizations: especially within the last 90 days requiring antibiotic therapy
Clinical Manifestations of Sepsis
- Signs and symptoms to an infectious source
- Arterial hypotension (SBP<90, MAP< 70)
- Temperature>38.3 or <36
- Heart Reate>90
- Tachypnea, respiratory rate > 20
What is the big Lab evaluation of Sepsis
Hyperlactemia: elevated serum lactate of >2
- Coagulation abnormalities’
- Thrombocyopenia
- Hyperbilirubinemia
Risk factors for community acquired MRSA infections include
- Participation in contact sports
- Millitary Service
- Incarceration
- Injection drug use
What is the most common cause of Tonsillopharyngitis, and bacterial pharyngitis in children and adolescents
Streptococcus Pyogenes
Main symptoms and risk factors for acquisition of infection of Mycobacterium Tuberculosis
Main symptoms:
- Productive cough
- Hemoptysis
- Fatigue
- Weight Loss
- Fever
- Night Sweats
Risk Factors of infection -Household Exposure -Incarceration -Recreationa; i;llicit drug abuse Traverl to an endemic aarea
Risk Factors for reactivation and drug resistance for TB
Reactivation:
- Gastrecomy
- Silicosis
- Diabetes Mellitus
- HIV
- Immunosuppressive drugs
Risk factors for drug resistace
- immigration from endemic region
- close contact with infected individual
- unsucessful therapy
- patient noncomplient
Clinical Manifestations of TB
- Cough most Common symptom
- Blood streaked sputum
- slowly progressive constitutional symptoms
- chronically ill’
- chest examination is nonspecific and post tussive atypical rales are classic
what is the difference between CMV infection and infecious mononucleosis:
CMV does not have the pharyngeal symptoms
very unnusual to have pharyngeal symptoms in Acute CMV
also in immunocomprimised individuals will appear with negative heterophil antibodies
is there a difference between CMV infecftion and disease?
yes! CMV disease has symptoms and signs always usually as a viral syndrome
characteristics of Perinatal disease and CMV inclsion disease?
Jaudice, hepatosplenomeagly, thrombocytopenia, purpura, microcephaly, periventricular CNS altercations, Mental retardaftion, and motor disabillity
Hearing loss develops in greater than 50 percent of infacnts who are symptomatic at birth
Most infected neonates are asymptomatic but neurologic deficts may ensue later in life including hearing loss and mental retardation
Characteristic symptoms pf Primary Coccidioidomycosis
Arthralgias with periarticular swelling of knees annd ankles
Erythema nodosum can develop 2-20 days after symptoms start
How does disseminated Coccidioidomycosis present in HIV infected patients
more often shows pulmonary miiliary infiltrates, lymphadenopathy, and meningitis but skin lesions are uncommon
What are signs and symptoms of malaria?
Anemia Jaundice Splenomegaly Mild Hepatomegaly Hypotension Seizure
typical begins with Prodrome headache and fatigue followed by fever usually irregulr
- 48 hour cycles are Pvivax and P ovale
- 72 hour cyces P malarie
Myalgias arthalgias Cough chest pain abdominal pain anorexia nausea vo,iting and diarrhea seizures may represent simple febrile convulsions or evidence of severe neurologic disease
Clinical manifestations of Multiple Myeloma
Symptoms of anemia
Lytic bone lesions’symptoms of kidney failure
Soft tissue masses
