Important Antimicrobial classes based on mode of action Flashcards

1
Q

Cell Wall/Cell Membrane

A
  • Beta lactams (penicillin, ampicillin, cephalosporins, carbapenems, monobactams)
  • Glycopeptides (Vancomycin)
  • Bacitracin
  • Polymyxin
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2
Q

Nucleic acid synthesis inhibitor

A
  • Sulfonamides/ trimethoprim-Folic acid synthesis (Purine metabolism)
  • Nitroimidazoles/Nitrofurans
  • Fluoroquinolons (enrofloxacin, ciprofloxacin)
  • Novobiocin
  • Rifampin (RNA)
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3
Q

Protein synthesis

A
Tetracyclines
Macrolides
Aminoglycosides
Chloramphenicol
Lincosamides
Streptogramins
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4
Q

Antifungal

A

Polyens
Azoles
(targets ergosterols)

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5
Q

Beta lactams (penicillin, ampicillin, cephalosporins, carbapenems, monobactams)

A

Cell Wall/Cell Membrane

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6
Q

Glycopeptides (Vancomycin)

A

Cell Wall/Cell Membrane

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7
Q

Bacitracin

A

Cell Wall/Cell Membrane

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8
Q

Polymyxin

A

Cell Wall/Cell Membrane

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9
Q

Sulfonamides/ trimethoprim-Folic acid synthesis (Purine metabolism)

A

Nucleic acid synthesis inhibitor

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10
Q

Nitroimidazoles/Nitrofurans

A

Nucleic acid synthesis inhibitor

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11
Q

Fluoroquinolons (enrofloxacin, ciprofloxacin)

A

Nucleic acid synthesis inhibitor

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12
Q

Novobiocin

A

Nucleic acid synthesis inhibitor

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13
Q

Rifampin

A

Nucleic acid synthesis inhibitor

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14
Q

Tetracyclines

A

Protein synthesis

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15
Q

Macrolides

A

Protein synthesis

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16
Q

Aminoglycosides

A

Protein synthesis

17
Q

Chloramphenicol

A

Protein synthesis

18
Q

Lincosamides

A

Protein synthesis

19
Q

Streptogramins

A

Protein synthesis

20
Q

Polyens

A

Antifungal

21
Q

Azoles

A

Antifungal