Implantation Flashcards
How much time does the embryo spend in the fallopian tube?
3 days
What is the blastocoele?
The vacuolized space adjacent to the inner cell mass
What is decidualization?
The morphological and biochemical differentiation of uterine stroma
It is characterized by the accumulation of glycogen and lipds, activation of COX-2, recruitment of dNK cells, and production of prolactin and IGFBP-1
COX-2 stimulates increased synthesis of _________.
PGE2
It’s thought that decidualization results from __________ signalling.
progesterone and estrogen
Trophoblasts secrete __________.
bHCG
True or false: the zona pellucida merges with the endometrium.
False. The blastocyst “hatches” on day 5 from the zona pellucida and implants in the endometrium. It is believed that there is a lytic agent in the uterine cavity that causes this. This depends on a morula/blastocyst - unfertilized eggs dont hatch
When (in the cycle) is the uterus receptive for implantation?
Day 20-24
What are pinopods?
Microvilli on the endometrial surface that aid in implantation
The first step in implantation is _______________.
apposition
The uterine stroma just deep to the embryo is called the ___________ and the uterine stroma just superficial to the embryo is called the __________ and the uterine stroma next to the myometrium is called the _________.
decidua basalis; decidua capsularis, decidua parietalis
Where is the most common site of implantation?
The posterior wall of the uterus, just superior to the fundus
______________ is when the placenta obscures the cervix.
Placenta previa
What is placenta accreta?
When the placenta grows deep into the walls of the uterus
The leading cause of maternal death in the first trimester is _____________.
ectopic pregnancy