IMMUNOPHENOTYPES Flashcards
CD34+
Blasts
CD34+, CD33+
Myeloid Blasts
TdT+, CD10+
Lymphoid Blasts
CD19+, CD20+
B-Lymphocytes/Blasts/Lymphoma
CD3+, CD5+
T-Lymphocytes/Blasts/Lymphoma
TdT+, CD34+, CD10+, CD20 -
ETV6-RUNX1
*B-ALL (B cell Acute Lymphoblastic Leukemia)
CD10+, TdT+
BCR-ABL
*Acute Lymphoblastic Leukemia
CD10-, TdT+
MLL
*Acute Lymphoblastic Leukemia
Light Chain Restricted (Kappa or Lambda)
CD20 weak
CD5+
CD23+
Chronic Lymphocytic Leukemia (CLL)
Light Chain Restricted (Kappa or Lambda) CD20 weak CD5+ CD23+ ZAP-70
Chronic Lymphocytic Leukemia (CLL)
**BAD prognostic Indicator (ZAP-70)
Light Chain Restricted (Kappa or Lambda) CD20 weak CD5+ CD23+ CD38
Chronic Lymphocytic Leukemia (CLL)
**BAD prognostic Indicator (CD38)
Light Chain Restricted (Kappa or Lambda)
CD20 STONG
CD5+
CD23 -
IgH;Cyclin D1
*MCL (Mantle Cell Lymphoma)
CD10
CD19
CD20
Burkitt Lymphoma (endemic or sporadic)
Light Chain Restricted CD38+++ CD138+++ CD19- CD20-
Plasma Cell Neoplasms
**Most often involve IgH translocation
CD30-
CD15-
CD20+
CD3 surrounding R/S
Nodular Lymphocyte Predominant Hodgkin Lymphoma