GENOTYPES Flashcards
1
Q
t(15;17)(q22;q12)
A
PML-RARA
*AML - DIAGNOSTIC by itself
2
Q
t(8;21)(q22;q22)
A
RUNX1-RUNXT1
*AML- DIAGNOSTIC by itself
3
Q
t(12;21)(p13;p22)
A
TEL-AML1
*ALL
4
Q
Cytogenet (-)
A
FLT3 mutation (+)
*AML
5
Q
inv(16)(p13.1;q22)
A
CBFB-MYH11
•AML - DIAGNOSTIC by itself
6
Q
t(9;22)(q34;q11.2)
A
BCR-ABL1
*ALL
7
Q
t(v;11q23)
A
MLL rearranged
*ALL
8
Q
t(12,21)(p13;q22)
A
TEL-AML1 (ETV6-RUNX1)
*ALL
9
Q
Hyperdiploid (greater than 50 chromosomes)
A
*ALL
10
Q
Jak2V617F mutation
A
Polycytopenia Vera
11
Q
del13q14.3
A
Chronic Lymphocytic Leukemia (CLL)
12
Q
del13q14.3 and 17p
A
Chronic Lymphocytic Leukemia (CLL)
***BAD prognostic Indicator
13
Q
t(11;14)(q13;q32)
A
IgH;Cyclin D1
*MCL (Mantle cell lymphoma)