Immunopathology IV Flashcards
kaposi sarcoma is associated with what type of herpes
HHV8
what does kaposi sarcoma look like
painful purple or brown cutaneous nodules
what types of drugs can you use to treat HIV
reverse transcriptase inhibitors
integrates inhibitors
protease inhibitors
amyloidosis
diverse group of disorders characterized by extracellular deposition and accumulation of abnormal misfolded protein material
what does amyloidosis look like under congo red
apple colored
what are the 2 components of amyloid
amyloid protein fibrils
pentagonal component
amyloid protein fibrils
have teh capacity to fold into a beta pleated sheet configuration with binding sites for Congo red
pentagonal component
glycoprotein related to normal serum protein
amyloid pathogensis
often systemic
how is amyloidosis calssified
distribution of amyloid deposites
prsence or absense of preexisting disease
chemical type of amyloid protein fibril
what is amyloid light chain type composed of
Ig light chains - often gamma
what type of amy,oid in most common
amyloid light chain type
what is the organ distribution of amyloid light chain type
generalized tends to involved heart, GI, peripheral nerves, skin and tongue
what does amyloid associated occur with
inflammatory or infectious states
what is amyuloid associated called
reactive or secondary
