Immunoloy

Question 1

What is characteristic of a primary response compared to a secondary response?

Answer 1

More IgM antibodies are produced in the primary response

Question 2

Which cell is capable of immunologic memory?

Answer 2

B lymphocytes (B cells)

Question 3

What is known as the helper T cell?

Answer 3

CD4

Question 4

What is know as the cytoxic T cell?

Answer 4

CD8

Question 5

this is the region that binds to the receptors on phagocytic cells:

Answer 5

FC fragment

Question 6

This is the region has the antibody binding site?

Answer 6

FAB

Question 7

The portion of an immunoglobulin molecule that controls antigen binding to the antibody:

Answer 7

the variable sequences in the V region

Question 8

Which cells are involved in cell mediated immunity?

Answer 8

T-Cells

Question 9

Which cells are involved in humoral mediated immunity?

Answer 9

B-Cells

Question 10

The type of immunity that follows the injection of an immunogenic (vaccination) is termed:

Answer 10

artificial active immunity

Question 11

Individual infected with mircororganims produces Ab (clinical or subclinical infection)

Answer 11

Naturally acquired active immunity

Question 12

Individual protected by abs produced by another person (maternal abs that cross placenta and are present in breast milk)

Answer 12

Naturally acquired passive immunity

Question 13

individual received immune globulin containing abs produced by another person (Rhogam)

Answer 13

Artificically acquired passive immunity

Question 14

A reactive total anti-HBc and reactive HBsAg indicate what about the hepatitis infection?

Answer 14

Chronic HBV infection

Question 15

HBsAg and HBeAg postive indicate what?

Answer 15

acute infection

Question 16

Anti- HBe and Anti HBs indicate what?

Answer 16

recovery

Question 17

What pathway is Ab indepent. Activated by bacteria, fungi, viruses, tumor cells, some parasites?

Answer 17

Alternative pathway

Question 18

What path way is triggered by ag/ab rxn. IgM is most efficient activator?

Answer 18

Classical pathway

Question 19

What are the functions of complement pathway?

Answer 19

inflammation, opsonization, chemotaxis, cell lysis

Question 20

C5-C9 are which part of the the pathway?

Answer 20

Membrane attack complex (lysis)

Question 21

Cells that can act as antigen presenting cells for exogenous antigens include?

Answer 21

B lymphocytes

Question 22

This enhances cytolytic activity of lymphokine-activated killer cells (LAK)

Answer 22

IL-2

Question 23

Defense mechanism present at birth. not ag specific

Answer 23

innate or natural immunity

Question 24

Defense mechanism that are antigen specific

Answer 24

adaptive or acquired immunity

Question 25

What is characteristic of an anamnestic repsonse versus a primary response?

Answer 25

Has a longer plateau

Question 26

What can cause a false VRDL test?

Answer 26

SLE

Question 27

The major clinical manifestation of a B-cell deficiency is:

Answer 27

recurrent bacterial infections

Question 28

what type of sensitivity invovles IgE and anaphylaxis?

Answer 28

Type 1

Question 29

What type of sensitivity involves AB mediated cells surface reactions?on the surface of cells (hematuria and decreased Hgb) Transfusion reactions, hemolytic disease of newborn, autoimmune hemolytic anemia

Answer 29

Type II

Question 30

This type of hypersensitivity is in the tissues? | SLE and RA

Answer 30

Type III

Question 31

This type of hypersensitivity is cell mediated? | Contact dermatitis, hypersensitivity pneumonitis, TB skin test

Answer 31

Type IIII

Question 32

These cells recognize target cells in the absence of MHC proteins?

Answer 32

NK cells

Question 33

A syphillis test that detects specific treponemal antibodies?

Answer 33

FTA-ABS

Question 34

Prozone is an excess of what?

Answer 34

antibody

Question 35

Postzone is an excess of what?

Answer 35

antigen

Question 36

The serum of a patient who recieved all doses of the hepatitis B vaccine should contain:

Answer 36

anti-HBs

Question 37

A decreased CH50, normal C3 and C4 levels is a problem in which part of the pathway?

Answer 37

C5-C9

Question 38

What immunoglobulins are expressed on the surface of a mature unstimulated B lymphocyte?

Answer 38

IgD and IgM

Question 39

Which complement regulatory protein acts to prevent initial complement activation?

Answer 39

C1 inhibitor

Question 40

What disease has depostitions of immune complexes in the kidney?

Answer 40

SLE

Question 41

What auto-immune disorder is indicated by an increased titer of anti-Sm (anti-smith) antibodies?

Answer 41

SLE systemic lupus erythematosus