Immunology Overview Exam 1 Flashcards

1
Q

What are two examples of physical barriers?

A

Skin 2m squared

Mucous membranes 400m squared

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2
Q

Non-specific defense of the body

A

Innate immune system

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3
Q

Specific defense of the body involving cognant antigen

A

Adaptive immune system

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4
Q

What are 3 examples of cell types in the innate immune system?

A

Monocytes/macrophages
Neutrophils
Natural killer cells

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5
Q

Which system is inflammation classified under?

A

Innate immune system

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6
Q

What are 2 examples of cell types in the adaptive immune system?

A

B cells

T cells

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7
Q

What are antibodies?

A

B cells

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8
Q

Do B cells kill?

A

No, mark target for destruction (opsonize)

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9
Q

In adaptative immune system, what is the basis for immunization?

A

Memory

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10
Q

Antibodies and T cell receptors looking for their match to bind to which allows proliferation

A

Cognant antigen

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11
Q

What are some antigen presenting cells required by T cells for activation?

A

Dendritic cells
Macrophages
B cells

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12
Q

Hormone like messengers produced especially by T helper cells that communicate with other cells

A

Cytokines

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13
Q

Examples of cytokines

A

Interleukins, interferon, tumor necrosis factor

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14
Q

What causes a hypothalamic fever response?

A

IL-1

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15
Q

What functions as a billboard to display peptides?

A

Major histocompatibility complex

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16
Q

Where is MHC class I found?

A

All cells of the body

Scanned by killer T cells so they can kill virus infected cells

17
Q

Where is MHC class II found?

A

Antigen presenting cells

Displays what has been killed at battle site and informs T helper cells

18
Q

Describe the antigen receptors in innate immune response

A

Precisely tuned to recognize common pathogens

19
Q

Describe the antigen receptors in adaptive response

A

Unfocused looking for cognant antigen