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Immunology > Immunology Exam 3 > Flashcards

Immunology Exam 3 Flashcards

1
Q

Co-stimulation is?

A

a. Antigen presentation
b. Additional signaling to lymphocytes
c. Reactivation of the foreign pathogen in the primary lymphoid tissue
d. Inactivation of the pathogen in the secondary lymphoid tissue
e. None of the above

B

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2
Q

What are examples of co-receptors for T-cells?

A

a. CD4
b. CD8
c. B7
d. A and b
e. A and c

D

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3
Q

What is a co-stimulatory receptor for T cells?

A

a. CD4
b. CD8
c. B7
d. CD28
e. None of the above

D

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4
Q

In the lymph node, naive B cells are located in the?

A

a. Cortex and primary follicles
b. Paracortex and primary follicles
c. Medulla and primary follicles
d. Secondary follicle
e. None of the above

A

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5
Q

Which cells can express B7?

A

A. All nucleated cells
B. All cells except dendritic cells
C. All cells except dendritic cells and macrophages
D. All cells except B cells
E. Only dendritic cells, macrophages and B cells

E

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6
Q

Which antibodies protect against parasite infections?

A

a. IgM
b. IgG
c. Monomeric IgA
d. Dimeric IgA
e. IgE

E

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7
Q

Which receptor is structurally similar to CD28?

A

a. CD4
b. CD8
c. CTLA4
d. CD3
e. None of the above

C

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8
Q

Which interleukin is essential for the proliferation and differentiation of lymphocytes?

A

a. IL-1
b. IL-2
c. IL-3
d. IL-4
e. None of the above

B

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9
Q

What are NOT the features of naïve B-cells?

A

a. Surface immunoglobulins
b. Surface MHC class II molecules
c. High rate Ig secretion
d. Proliferation
e. Somatic hypermutation

C

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10
Q

Which cells express CD40?

A

a. DC
b. MF
c. B cells
d. All the above
e. None of the above

D

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11
Q

Macrophages in the lymph node

A

a. remove pathogens and their breakdown products
b. prevent infectious microorganisms from passing through the lymph node and gaining
access to the blood
c. eliminate lymphocytes that die by apoptosis during their maturation and selection
d. All the above
e. None of the above

D

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12
Q

Which cells express CD40L

A

a. T-helpers
b. T-suppressors
c. Cytotoxic T cells (T-killers)
d. Naïve B cells
e. Differentiated B cells

A

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13
Q

Which cells cannot capture, process and present an antigen to T cells?

A

a. DC
b. CD4+ T cells
c. B cells
d. All the above
e. None of the above

B

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14
Q

Which cells can be activated or regulated by CD4+ T-helper cells?

A

a. DC
b. MF
c. B cells
d. All the above
e. None of the above

D

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15
Q

What are the features of plasma cells?

A

a. Surface immunoglobulins
b. Surface MHC class II molecules
c. High rate Ig secretion
d. Proliferation
e. Somatic hypermutation

C

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16
Q

In the lymph node, T cells are located in the

A

a. Cortex
b. Paracortex
c. Medulla
d. Primary follicle
e. Secondary follicle

B

17
Q

Which antibodies protect the mucosal surfaces?

A

a. IgM
b. IgG
c. Monomeric IgA
d. Dimeric IgA
e. IgE

D

18
Q

Which Interleukin is an important mediator of fever induction?

A

a. IL-1
b. IL-2
c. IL-4
d. IL-6
e. IL-10

D

19
Q

Which antibodies are present in breast milk?

A

a. IgM
b. IgG
c. Monomeric IgA
d. Dimeric IgA
e. IgE

D

20
Q

T cell priming is

A

a. T cell activation
b. T cell maturation
c. Differentiation of CD4+ and CD8+ subpopulations
d. Formation of T memory cells
e. Communication form B cells to T cells

A

21
Q

Which T cells remain in the secondary lymphoid tissue after activation?

A

a. CD4+
b. CD8+
c. Regulatory T cells
d. Memory T cells
e. None of the above

A

22
Q

The adaptive immune response is generated in

A

a. Bone marrow
b. Thymus
c. Secondary lymphoid tissues
d. All the above
e. None of the above

C

23
Q

To initiate T-cell activation, the antigen is presented

A

a. By dendritic cells to naïve T cells in primary lymphoid tissues
b. By dendritic cells to naïve T cells in secondary lymphoid tissues
c. By macrophages to naïve T cells in primary lymphoid tissues
d. By dendritic cells to naïve B cells in primary lymphoid tissues
e. By dendritic cells to naïve B cells in secondary lymphoid tissues

B

24
Q

In the lymph node, differentiated B cells are located in the

A

a. Cortex
b. Paracortex
c. Medulla
d. Primary follicle
e. Secondary follicle

C

25
Q

What is a co-stimulatory ligand for T cells?

A

a. CD4
b. CD8
c. B7
d. CD28
e. None of the above

C

26
Q

Which T-cells suppress the immune response?

A

a. Th1
b. Th2
c. Th17
d. Tfh
e. Treg

E

27
Q

Which cells require stronger costimulatory activity?

A

a. B cells
b. Professional antigen-presenting cells
c. CD4+ cells
d. CD8+ cells
e. All the above

D

28
Q

Cross-presentation means that

A

a. DC can present antigens in the context of MHC class I molecules
b. DC can present antigens in the context of MHC class II molecules
c. DC can present antigens in the context of both MHC class I and II molecules
d. B cells can present antigens to naïve T cells to activate them
e. B cells can present antigens to T-helper cells to become activated

C

29
Q

Which of the following molecules do NOT belong to cytokines?

A

a. IL-1
b. Perforin
c. Granzymes
d. A and b
e. B and c

E

30
Q

What is a co-stimulatory receptor for B cells?

A

a. CD40
b. CD40L
c. B7
d. CD28
e. None of the above

A

31
Q

How do neutralizing antibodies work?

A

a. They serve as molecular adaptors
b. They activate complement
c. They enhance phagocytosis
d. They cover pathogens thus preventing them to bind to human cells and infect them
e. None of the above

D

32
Q

Which antibodies can cross placenta to protect the fetus BEFORE the birth?

A

a. IgG
b. IgM
c. IgA
d. A and b
e. A and c

A

33
Q

What is a co-stimulatory ligand for B cells?

A

a. CD40
b. CD40L
c. B7
d. CD28
e. None of the above

B

34
Q

Which antibodies neutralize microbial toxins and animal venoms?

A

a. IgG
b. IgM
c. IgA
d. A and b
e. A and c

E

Immunology (3 decks)

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