IMMUNOLOGY- Autoantibody

Question 1

This is the autoantibody for Myasthenia gravis

Answer 1

Anti- ACh receptor

Question 2

Anti- basement membrane make the diagnosis of…

Answer 2

Goodpasture syndrome

Question 3

For SLE, antiphospholipid syndrome these are the autoantibody

Answer 3

Anti-cardiolipin, lupus anticoagulant

Question 4

Anticentromere are specific in diagnosis of…

Answer 4

Limited scleroderma (CREST syndrome)

Question 5

Which autoantibody help to diagnose Pemphigus Vulgaris

Answer 5

Anti desmoglein

Question 6

For SLE these are the autoantibody

Answer 6

Anti dsDNA, anti-Smith

Question 7

This autoantibody is present in Type 1 Diabetes Mellitus

Answer 7

Anti-glutamate decarboxylase

Question 8

Anti-hemidesmosome are specific for…

Answer 8

Bullous pemphigoid

Question 9

Which autoantibody help in Drug induced lupus?

Answer 9

Antihistones

Question 10

For polyomyositis, dermatomyositis these are the autoantibodies

Answer 10

Anti Jo-1, anti SRP, anti Mi-2

Question 11

Which autoantibodies are found in Hashimoto Thyroiditis?

Answer 11

Antimicrosomal, antithyroglobulin

Question 12

In primary Biliary cirrhosis this autoantibody is found

Answer 12

Antimitochondrial

Question 13

Nonespecific autoantibody found in SLE

Answer 13

Antinuclear antibodies

Question 14

From which disease can we find Anti Scl 70?

Answer 14

Scleroderma (diffuse)

Question 15

Which other name does Anti Scl 70 receive?

Answer 15

Anti DNA topoisomerase I

Question 16

This autoantibody is found in Scleroderma (diffuse)

Answer 16

Anti DNA topoisomerase I

Question 17

In which disease can we find Anti smooth muscle?

Answer 17

Autoimmune hepatitis

Question 18

For Sjogren syndrome, which are the autoantibodies?

Answer 18

Anti SSA, Anti SSB (anti Ro, anti La)

Question 19

Which are the autoantibody for Graves disease?

Answer 19

Anti TSH receptor

Question 20

Which autoantibodies are found in Mixed connective tissue disease?

Answer 20

Anti U1 RNP (ribonucleoprotein)

Question 21

c-ANCA (PR3 ANCA) are found in…

Answer 21

Granulomatosis with polyangitis (Wegner)

Question 22

Which autoantibodies are found in Celiac disease?

Answer 22

IgA antiendomysial, IgA anti-tissue transglutaminase

Question 23

p-ANCA (MPO-ANCA) are specific for..

Answer 23

Microscopic polyangiitis, Churg Strauss syndrome

Question 24

In Rheumatic arthritis these are the autoantibodies

Answer 24

Rheumatoid factor (antibody, most commonly IgM, specific to IgG Fc region), Anti CCP