immunology and serology

Question 1

Which of the following is not involved in the acquired or adaptive immune response?
a, phagocytosis
b. production of antibody or complement
c. induction of immunologic memory
d. accelerated immune response upon subsequent exposure to antigen

Answer 1

A.

Question 2

Which cells are involved in the production of antibodies?
a. dendritic cells
b. T lymphocytes
c. B lymphocytes
d. macrophages

Answer 2

C.

Question 3

Which of the following cells is involved in antigen recognition following phagocytosis?
a. B lymphocytes
b. T lymphocytes
c. Macrophages
d. Granulocytes

Answer 3

B.

Question 4

The role of the macrophage during an antibody response is to:
a. make antibody
b. lyse virus-infected target cells
c. activate cytotoxic T cells
d. process antigen and present it

Answer 4

D.

Question 5

Which of the following immunoglobulins is produced in the primary immune response?
a. IgA
b. IgE
c. IgG
d. IgM

Answer 5

D.

Question 6

Which of the following immunoglobulins is produced in the secondary immune response?
a. IgA
b. IgE
c. IgG
d. IgM

Answer 6

C.

Question 7

Which of the following MHC classes are found on antigen presenting cells?
a. Class I
b. Class II
c. Class II
d. Class IV

Answer 7

B.

Question 8

Which of the following MHC classes encodes complement components?
a. Class I
b. Class II
c. Class II
d. Class IV

Answer 8

C.

Question 9

Which of the following immunoglobulins is most efficient at binding complement?
a. IgA
b. IgE
c. IgG
d. IgM

Answer 9

D.

Question 10

Which portion of the immunoglobulin molecules contains complement binding sites?
a. Heavy chain variable region
b. Light chain variable region
c. Heavy chain constant region
d. Light chain constant region

Answer 10

C.

Question 11

Which pathway is activated by the formation of antigen-antibody complexes?
a. Classical
b. Alternative
c. Lectin
d. Retro

Answer 11

A.

Question 12

Which of the following is known as the recognition unit in the classical complement pathway?
a. C1q
b. C3a
c. C4
d. C5

Answer 12

A

Question 13

Which of the following is known as the membrane attack complex in the classical complement pathway?
a. C1
b. C3
c. C4, C2, C3
d. C5b, C6, C7, C8, C9

Answer 13

D.

Question 14

Which of the following refers to the effect of an excess amount of antigen present in a test system?
a. Postzone
b. Prozone
c. Zone of equivalence
d. Endzone

Answer 14

A.

Question 15

Which of the following refers to the presence of an excess amount of antibody present in a test system?
a. Postzone
b. Prozone
c. Zone of equivalence
d. Endzone

Answer 15

B.

Question 16

Which of the following properties of antibodies is not dependent on the structure of the heavy chain constant region?
a. ability to cross placenta
b. isotype (class)
c. ability to fix xomplement
d. affinity for antigen

Answer 16

D.

Question 17

Molecules that promote the update of bacteria for phagocytosis are:
a. Opsonins
b. Cytokines
c. Haptens
d. Isotypes

Answer 17

A.

Question 18

Select the term that describes the unique confirmation of the antigen that allows recognition by a corresponding antibody:
a. Immunogen
b. Epitope
c. Avidity
d. Clone

Answer 18

B.