Immunology

Question 1

what are the first responders of WBC’s

Answer 1

Neutrophils

Question 2

what percent of WBCs are neutrophils

Answer 2

40-75%

Question 3

what does a neutrophil lobe look like

Answer 3

multi lobed nucleus polys

Question 4

what is in PUS

Answer 4

a mixture of dead neutrophils

Question 5

what does neutrophils contain

Answer 5

lysosomes with hydrolytic enzymes and oxidase

Question 6

what percent of WBC’s are basophils

Answer 6

0.5%

Question 7

what do basophils do

Answer 7

mediate allergic reaction

Question 8

what three things do basophils contain

Answer 8

heparin
histamine
bradykinin

Question 9

what causes basophils to release

Answer 9

released due to binding of IgE

Question 10

What percent of WBC’s are eosinophils

Answer 10

2%

Question 11

what do eosinophils defend the body against

Answer 11

worm infections- eg. pinworm

Question 12

esophils are highly phagocytic for what?

Answer 12

Ag-Ab complex

Question 13

what differentiates into macrophages in tissues

Answer 13

monocytes

Question 14

lymphocytes (30%) are what two cells

Answer 14

T cell and B cell

Question 15

what are mast cells similar to

Answer 15

basophils

Question 16

what do mast cells mediate

Answer 16

allergic reaction

Question 17

mast cell degranulation releases?

Answer 17

histamine
bradykinin
heparin
SRS-A slow reacting substances of anaphylaxis

Question 18

what prevents mast cell degranulation

Answer 18

cromyln sodium (intal) given for exercise induced astham

Question 19

name the 5 actions of phagocytic cells

Answer 19

margination
diapedesis
ameboid motion
chemotaxis
phagocytosis

Question 20

macrophages are derived from

Answer 20

monocytes

Question 21

where are macrophages present in

Answer 21

lymph nodes
lungs
liver (kupffer cells)
spleen
bone marrow

Question 22

what system do macrophages make to fight off infection

Answer 22

reticuloendothelial system/monocyte macrophage system

Question 23

what are the 3 main function providing first line of defense

Answer 23

phagocytosis
antigen presentation
cytokine production

Question 24

phagocytosis

Answer 24

ingest bacteria, virus other foreign particles by powerful oxidizing agents like