Immunology Flashcards

1
Q

interleukin responsible for fever

A

IL-1

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2
Q

interleukin responsible for T cell production

A

IL-2

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3
Q

interleukin responsible for bone marrow proliferation

A

IL-3

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4
Q

interleukin responsible for IgE and IgG production

A

IL-4

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5
Q

interleukin responsible for IgA production and macrophage activation

A

IL-5

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6
Q

interleukin responsible for release of acute phase reactants i.e. CRP

A

IL-6

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7
Q

interleukin responsible for recruitment of neutrophils

A

IL-8

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8
Q

interleukins responsible for down regulating immune response

A

TGF-b and IL-10

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9
Q

role of interferon Y

A

up regulating immune system
secreted in response to IL-12 for granuloma formation

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10
Q

what is responsible for cachexia in cancer patients

A

TNF-a

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11
Q

what is responsible for maintaining granulomas

A

TNF-a

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12
Q

IL responsible for granuloma formation

A

IL-12, interferon Y and TNF a

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13
Q

cell surface proteins secreted by helper T cells

A

CD4, CD40L, CXCRR4, CXRR, MHC II

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14
Q

cell surface proteins secreted by cytotoxic T cells

A

CD8, MHC I

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15
Q

cell surface proteins secreted by NK cells

A

CD 16, CD56

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16
Q

cell sruface proteins secreted by macrophages

A

CD14, CD40L, CCR5, B7, Fc and C3b receptor

17
Q

cell surface proteins secreted by B cells

A

Ig, CD19, CD20, CD21, B7

18
Q

cell surface protein secreted by haematopeotic stem cells

19
Q

cell surface protein from B cells that binds antigen

A

immunoglobulin (Ig)

20
Q

cell surface protein that HIV binds to

A

CXCR4/CRR4 (helper T cells)

21
Q

cell surface protein all T cells produce

22
Q

what cell surface protein from NK cells bind Fc portion of IgG

23
Q

what cell surface protein from macrophages is the receptor for for PAMP i.e. LPS

24
Q

what cell surface receptors from macrophages enhance phagocytic activity

A

Fc and C3b receptor

25
what cell surface receptors are expresed by regulatory T cells
CD4, CD25
26
complement responsible for activating classic complement pathway
IgG and IgM
27
complement is part of what type of immune response
innate immune response
28
complement responsible for opsonization
C3b + IgG
29
complements responisble for anaphylaxis
C3a, C4a, C5a
30
complement responsible for neutrophil chemotaxis
C5a
31
complement responsible for chemolysis
C5b9