Immunology Flashcards
Allergy
an abnormal or hypersensitive response of the
immune system to a substance introduced into the body
what are the most common cause of urticarial reactions in
adults
drugs
what are the most common cause of urticarial reactions in
children
food and infection
Several drugs used in dentistry and medicine can cause
allergic reactions such as
parabens
sulfites
allergy to latex
type I hypersensitivity
IgE antibody complexes form on the surface of mast cells, which causes sudden histamine
release from these cells
Type III hypersensitivity
The primary function of this system is to recognize and eradicate
antigens that are fixed in tissue or within cells
This system is involved in protection against viruses, tuberculosis, and
leprosy
These reactions are IgG- or IgM-mediated reactions that result
in destruction of the targeted cells by complement and
antibodies
type II hypersensitivity
type IV sensitivity
delayed hypersensitivity, involving the cellular immune system,
include infectious contact dermatitis, transplant rejection, graft-versus-host
disease
Patients with IgE mediated allergy can have what lab findings
elevated IgE levels and eosinophils
medical management of allergies include
desensitization with injection
steroids
antihistamines
the local anesthetic associated with the highest incidence of
allergic reactions
procaine
what broad group of anesthetics may cross react with each other
benzoic ester
what antibiotics is a common cause of drug allergy
Penicillin
Many people are allergic to what analgesic
salicylates
what is a narcotic analgesic that commonly is used in dentistry
Codeine
topical anesthetic agents can produce what type of hypersensitivity reaction
Type I
Hereditary angioedema is a condition that
can be provoked by
infection, stress,
dental surgery or trauma
Contact stomatitis
a delayed allergic reaction that is
associated with the cellular immune response in most cases
Rheumatologic Disorders
disorders of the rheumatic diseases that affect bones,
joints, and muscles
Rheumatologic diseases affect what areas
joint, synovium, cartilage, or connective tissues
Osteoarthritis
a degenerative disease
caused by natural wearing down of cartilage that leads to cartilage loss
Rheumatologic Disorders
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Osteoarthritis
Sjӧgren Syndrome
Rheumatoid Arthritis
an autoimmune disease of unknown origin that is
characterized by symmetric inflammation of joints, especially of the hands, feet, and
knees
A potential dental complication of RA
development of
an anterior open bite, caused by destruction of the condylar heads and loss of condylar height
Osteoarthritis (OA), or degenerative joint disease, is the most common form of arthritis
OA usually affects often-used joints, such as
hips, knees, feet, spine, and hands
Psoriatic arthritis (PsA)
inflammatory arthritis associated with the inflammatory skin condition, psoriasis
Giant Cell Arteritis
Giant cell arteritis (GCA) is a systemic vasculitis involving medium-sized and large
arteries, most commonly the extracranial branches of the carotid artery and specifically
the temporal artery
Lyme Disease
Lyme disease is a multisystemic
inflammatory disease caused by the tickborne spirochete Borrelia
burgdorferi
he most common cause of chronic pain in the U.S
Fibromyalgia
