Immunologists Flashcards

1
Q

Smallpox vaccines

A

1798- Jenner

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2
Q

Phagocytosis

A

1862- Haeckel

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3
Q

Live, attenuated chicken cholera and anthrax vaccines

A

1880-1881- Pasteur

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4
Q

Cellular theory of immunity through phagocytosis

A

1883-1905- Metchnikoff

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5
Q

Therapeutic Vaccination

First report of live “attenuated” vaccine for rabies

A

1885- Pasteur

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6
Q

Humoral theory of immunity proposed

A

1890- Von Behring, Kitasata

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7
Q

Demonstration of cutaneous (delayed-type) hypersensitivity

A

1891- Koch

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8
Q

Antibody formation theory

A

1900- Ehrlich

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9
Q

Immediate-hypersensitivity anaphylaxis

A

1902- Portier, Richet

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10
Q

Arthus reaction of intermediate hypersensitivity

A

1903- Arthus

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11
Q

Hypothesis of antigen-antibody binding

A

1938- Marrack

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12
Q

Hypothesis of allograft rejection

A

1944

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13
Q

Development of polio vaccine

A

1949- Salk, Sabin

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14
Q

Vaccine against yellow fever

A

1951- Reed

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15
Q

Graft-versus-host reaction

A

1953

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16
Q

Clonal selection theory

A

1957- Burnet

17
Q

Interferon

A

1957

18
Q

Human leukocyte antigens (HLAs)

A

1958-1962

19
Q

T-cell and B-cell cooperation in immune response

A

1964-1968

20
Q

Identification of antibody molecule

A

1972

21
Q

First monoclonal antibodies

A

1975- Köhler

22
Q

Identification of genes for T cell receptor

A

1985-1987

23
Q

Monoclonal hepatitis B vaccine

A

1986

24
Q

Identification of toll-like receptors

A

1996-1998

25
Q

FOXP3 gene, the gene directing regulatory T cell development

A

2001

26
Q

Development of human papillomavirus vaccine

A

2005- Frazer