Immunoglobulins Flashcards

1
Q

What is the function of IgG

A

Main Ig in acquired immunity

  • Has the capability to cross placental barrier
  • High levels in chronic infection
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2
Q

What is the function of IgM

A
  • Part of the membrane receptor of naïve B lymphocytes (BCR)
  • Form found in the serum, secreted early in acquired immune response
  • Conc is high during early infection
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3
Q

What is the function of IgA

A
  • Found in GI, resp and urogenital tract mucosa and breast milk, tears and saliva
  • Prevents the colonization by pathogens
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4
Q

What is the function of IgD

A

-Membrane Ig, part of BCR Immune integrity→ increased in myelomas

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5
Q

What is the function of IgE

A

Involved in all allergic and parasitic processes

-Interacts with basophils and mast cells to cause histamine release

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6
Q

Which is the heaviest Ig

A

IgM

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