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Immuno 2 > Immunoglobulin Isotypes > Flashcards

Immunoglobulin Isotypes Flashcards

1
Q

IgA

A

Prevents attachment of bacteria and viruses to mucous membranes. Does not fix complement. Released in secretions. Breast milk.

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2
Q

IgM

A

Produced in the 1’ (immediate) response. Fixes complement. Does not cross placenta. Antigen receptor on surface of B cells. Pentamer when secreted.

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3
Q

IgD

A

Unclear function. Found on surface of B cells.

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4
Q

IgE

A

Binds mast cells and basophils. Cross-links. Immediate hypersensitivity. Release histamine. Activates eosinophils. Lowest concentration in serum.

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5
Q

IgG

A

Main antibody in 2’ (delayed) response to an antigen. Most abundant isotype in serum. Fixes complement. Crosses the placenta (passive immunity for infants). Opsonizes bacteria. Neutralizes bacterial toxins and viruses.

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Immuno 2 (4 decks)

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