Immunoglobulin (antibody) classes Flashcards
Most abundant antibody?
IgG (80%)
Function of IgG
Protects against bacteria and viruses by enhancing phagocytosis, neutralising toxins and triggering complement
Which is the only type of antibody that can cross the placenta?
IgG
The second antibody involved in the primary response?
IgG
First/most abundant antibody in the secondary response?
IgG
Mainly found in sweat, tears, saliva, mucus, breast milk and GI secretions
IgA
Levels decrease during stress, lowering resistance to infection
IgA
Type III reactions involve antigens, antibodies and complement - which antibody?
IgG
Occurs as pentamers
IgM
First antibody class to be secreted by plasma cells after initial exposure to any antigen
IgM
In blood plasma, anti-A and anti-B antibodies of the ABO blood group, which bind to A and B antigens during incompatible blood transfusions are also?
IgM
First antibody involved in primary response
IgM
Mainly found on the surfaces of B cells as antigen receptors
IgD
Less than 0.1% of all antibodies
IgE
Located on mast cells and basophils
IgE