Immunodeficiencies

Question 1

An infant has an immunodeficiency making him especially susceptible to enteroviruses among other problems. Which cell type of immunodeficiency does he probably have?

Answer 1

B cell deficiency

Question 2

A two year old has Neisseria meningitidis sepsis. Which type of immunodeficiency should you test for?

Answer 2

Terminal compliment deficiency

Question 3

List four combined B/T cell deficiencies.

Answer 3

SCID
Wiskott-Aldrich
Bloom syndrome
Nijmegen breakage syndrome

Question 4

A child with SCID has immunodeficiency involving which general immune system cell types?

Answer 4

B and T

Question 5

Nijmegen breakage syndrome involves which immune system cell types?

Answer 5

B and T

Question 6

Bloom syndrome involves which immune system cell types?

Answer 6

B and T

Question 7

A toddler in your office presents with recurrent abscess and was treated 1 year ago for a hepatic abscess. What type of immune deficiency should you test for?

Answer 7

Phagocytic disorders such as chronic granulomatous disease (inability to mount an oxidative burst.)

Question 8

List some organisms commonly causing infection in phagocytic disorders.

Answer 8

Staph aureus
Serratia
Aspergillus
Crhomobacterium
Burkholderia
Nocardia