Flashcards

Question 1

What substances are most commonly associated with anaphylactoid reactions? Are these mediated by IgE?

Answer 1

NSAIDs
Aspirin
Radiographic contrast

Question 2

Previously sensitized T cells interact with an antigen causing an inflammatory reaction that peaks in 24-72 hours. What type of hypersensitivity is this?

Answer 2

Type IV cell mediated.

Question 3

What type of hypersensitive is seen in antibody-antigen mediated reactions?

Answer 3

Type III as in RA, some drug reactions.

Question 4

What is the most likely diagnosis in a child with the following scenario: he was just started on PCN, has never had it before, he develops the following after 8 days:

Fever 
Nausea/vomiting
Skin rash with redness, itching, urticaria, angioedema
Joint pain of the knees and ankles
Lymph node swelling
Muscle aches
Proteinuria

Answer 4

Serum sickness which is a type III hypersensitivity reaction.

Question 5

In infants with atopic dermatitis, what is the typical skin distribution of lesions?

Answer 5

Extensor

Question 6

Anaphylaxis to an allergen is mediated by what immunoglobulin?

Answer 6

IgE