immunodeficiencies

Question 1

3 B-cell disorders

Answer 1

x-linked Bruton agammaglobulinemia
selective IgA deficiency
common variable immunodeficiency

Question 2

defective BTK gene

Answer 2

x-linked Bruton agammaglobulinemia

Question 3

decreased IgA
normal IgG and IgM

Answer 3

selective IgA deficiency

Question 4

false positive b-hCG

Answer 4

selective IgA

Question 5

increased susceptibility to giardia (b-cell)

Answer 5

selective IgA

Question 6

recurrent bacterial and enteroviral infections after 6 months

Answer 6

bruton agammaglobulinemia

Question 7

live vaccines contraindicated

Answer 7

bruton agammaglobulinemia

Question 8

defective b-cell differentiation

Answer 8

CVID

Question 9

low plasma and immunoglobulins

Answer 9

CVID

Question 10

4 T-cell disorders

Answer 10

DiGeorge
IL-12 receptor deficiency
job syndrome (AD hyper-IgE)
chronic mucocutaneous candidiasis

Question 11

4 B and T cell disorders

Answer 11

SCID
ataxia telangiectasia
hyper-M syndrome
wiskott-aldrich

Question 12

failure to thrive, chronic diarrhea, thrush
recurrent bacterial, viral, fungal and protozoal infx

Answer 12

SCID

Question 13

decreased t-cell receptor excision circles (TREC)

Answer 13

SCID