Immunodeficiencies Flashcards
Coarse facies
Cold abscesses
increased IgE
Eczema
Job syndrome
Hyper IgE
Increased autoimmune disease risk
Bronchiectasis
Lymphoma
Sinopulmonary infections
Common variable immunodeficiency
Recurrent bacterial and enteroviral infections after 6th month
X-linked (Bruton’s) agammaglobulinemia
Tetany
Recurrent viral/fungal infections
Conotruncal abnormalities
DiGeorge’s syndrome
Disseminated mycobacterial and fungal infections
May present after administration of BCG vaccine
IL-12 receptor deficiency
Asymptomatic, but can see autoimmune disease, atopy, anaphylaxis to IgA containing products
Selective IgA deficiency
Noninvasive candida albicans infections and mucous membranes
Chronic mucocutaneous candidiasis
FTT
Chronic diarrhea
Thrush
Recurrent infections
SCID (Treat w/ bone marrow transplant)
Ataxia, spider angiomas, IgA deficiency
Ataxia-telangiectasia
Pneumocystis, cryptospordium, CMV opportunistic infections
Hyper-IgM
Thrombocytopenic purpura
Eczema
Recurrent infections
Wiskott aldrich syndrome
Recurrent skin and mucosal bacterial infections
Absent pus formation
Impaired wound healing
Leukocyte adhesion deficiency
Recurrent pyogenic infections by staphylococci and streptococci Partial albinism Peripheral neuropathy Progressive neurodegeneration Lymphohistiocytosis
Chediak Higashi
Increased susceptibility to catalase positive organisms
Chronic granulomatous disease
