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Medikamenter > Immunmodulerende > Flashcards

Immunmodulerende Flashcards

1
Q

Filgrastim

A

Neupogen® / Nivestim® / Tevagrastim® / Zarzio®

CSF3-analog (granulocytt-CSF).

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2
Q

Glatirameracetat

A

Copaxone®

Polymer av aminosyrer. Ligner på myelin basic protein (MBP).

Man tror det aktiverer supressor-T-celler (spesifikke for et myelinantigen).

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3
Q

Mykofenolat

A

CellCept®

Inosinmonofosfatdehydrogenase-hemmer.

Hemmer de novo guanosinnukleotidsyntese og derved purinsyntesen. Rammer først og fremst lymfocytter fordi andre celletyper utnytter hjelpebaner.

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4
Q

Sirolimus

A

Rapamune®

Hemmer aktivering av mTOR (en regulatorisk kinase).

Hemmer aktivering og proliferasjon av antigen- og cytokinstimulerte T-celler: hemmer antistoffproduksjon.

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Medikamenter (5 decks)

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