immunization Flashcards
carrier protein that enhances immunologic response
conjugating proteins
saline, sterile water
suspending fluids/vehicles
common preservative used especially in multiple doses that kill orminhibit growth of microorganism
thimerosal
aluminum salt to increased immunogenicity and prolong stimulatory effect
adjuvants
administration techniques
intradermal
subcu
intramuscular
Philippines EPI vaccines
BCG hep B DTwP Hib Hep B OPV rotavirus PCV maseles MMR/MR Td
live vaccine given at earliest time possible
Bacillus Calmette Guarin
dosage of BCG
.05 mL ID / .1 mL ID
PPD is not necessary for healthy infants >2 months not given BCG at birth unless
suspected congenital TB
clinical and xray siggestive og TB
history fo close contact to suspected and known cases
contraindications of BCG
immunodef
progressive dermatoses near site of infection
adverse rxns of BCG
abscess
regional lymphadenopathy
osteitis affecting epiphysis of long bones
usual and accelerated rxns of induration of BCG
2-4weeks; 2-4 days
usual and accelerated rxns of pustule formation of BCG
5-7 wks; 5-7 days
usual and accelerated rxns of scar formation in BCG
2-3mos; 2-3 wks
Hep B: active or inactived?
inactivated
dose of Hep B
- 5 mL IM (10 mcg)
1. 0 mL IM (20 mcg)
schedule of hep B
birth-6-10-14 weeks
0-1-6 mos
adverse rxn of hep B
pain
swelling
what to do if mother is HBsAg
- 5 ml IM Hep B vaccine @ birth within 12 hrs
0. 5 mL IM HBIg within 12 hrs
breastfeeding: risk or no risk for hep B virus?
no risk with appropriate administration of vaccine and Ig
DTP: which are toxoids
DT
DTP: which are whole cell inactivated or killed vaccine or accelular pertussis
P
pertussis vaccine may be
whole cell or acellular
dose of DTP
0.5 mL IM
schedule of DTP
6-10-14 wks
4th dose @ 1yr after 3rd
5th dose @ 4-6yrs
usual rxns for DTP
low fever 72hrs
restlessness
irritability
pain and swelling
adverse rxns of DTP
high fever seizure sever irrita somnolence lethargy uncontrolabble crying
if a patient develops any of the DTwP, what to do
recommended nxt dose of DTaP
OPV: live or inactivated?
live
schedu of OPV
6-10-14 wks
4th dose @ 12-18 mos
5th dose @ 4-6 yrs
administartion of OPV
oral
contraindications for OPV
altered immune antineoplastics or chemo high dose steroids HIV prgs on radiation contact with immunocom patients
advwerse of OPV
paralysis
IPV: live or ianctivated
inactivated