Immunity

Question 1

what is a key feature of immunity

Answer 1

cells must be able to discriminate self from non-self

Question 2

what is innate immunity

Answer 2

immunity present from birth, which is instinctive, non-specific and does not depend on lymphocytes

Question 3

what is adaptive immunity

Answer 3

immunity is specific and acquired, and requires lymphocytes and antibodies

Question 4

what 3 components make up innate immunity

Answer 4

physical and chemical barriers
phagocytic cells
blood proteins (complements and acute phase)

Question 5

why do we need adaptive immunity

Answer 5

Microbes evade innate immunity (proteases and decoy proteins which innate immunity would not pick up on)
memory is needed for a faster response
innate immunity is not able to tackle intracellular microbes

Question 6

is T cells intracellular or extracellular and is B cells intracellular or extracellular

Answer 6

T cells - intracellular

B cells - extracellular

Question 7

where are T and B cells produced

Answer 7

Bone marrow

Question 8

where does T cells mature

Answer 8

Thymus

Question 9

what is the major histocompatibility complex (MHC)

Answer 9

mechanism in which the immune system is able to identify self from non self, as all body cells have a specific collection of glycoproteins on the surface, which is unique in all individuals

Question 10

What is MHC referred to in humans

Answer 10

human leukocyte antigens

Question 11

what is T cell selection

Answer 11

the process where T cells that recognise SELF are killed in the foetal thymus